Compare Nesina vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nesina
(alogliptin)

Januvia
(sitagliptin)

Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
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Coupons for Nesina
Best available price for 30 (25mg) tablets of alogliptin
Coupons for Januvia
Best available price for 30 (100mg) tablets of januvia
Reviews & ratings
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Have you used Nesina (alogliptin)?
Worth itNot sureNot worth it
Reviews for Januvia
44%
+56% better vs. Nesina
34%
+66% better vs. Nesina
17%
+17% better vs. Nesina
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it
Side effects
NesinaJanuvia

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
  • Common cold 2%
  • Diarrhea 1%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »
How it works
NesinaJanuvia
alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.
Type of medication
NesinaJanuvia
Prescription only
Available as
NesinaJanuvia
  • Pill
  • Pill
Used for
NesinaJanuvia
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
NesinaJanuvia
    Detailed Nesina (alogliptin) risks & warnings »
    • History of pancreatitis
    • High blood triglyceride levels
    • Gallstones (stones in gallbladder)
    • History of alchoholism
    • Kidney problems
    Detailed Januvia (sitagliptin) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    NesinaJanuvia
    No food related info.
    • Take once a day in the morning with or without food.
    Kidneys and liver
    NesinaJanuvia
    No kidneys and liver related info.
    • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
    Pain
    NesinaJanuvia
    No pain related info.
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    Weight
    NesinaJanuvia
    No weight related info.
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    Upsides and benefits
    NesinaJanuvia
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • Rarely causes low blood sugar.
    • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
    • Oral blood sugar-lowering medicine.
    • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
    • Uses the hormones naturally produced by your body to affect how sugar is processed.
    • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
    Downsides and risks
    NesinaJanuvia
    • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
    • Likely expensive since there's no generic version available.
    • Some people might get frequent throat infections or nasal congestion.
    • Lowers A1c (average blood sugar over time) by less than 1%.
    • Available as brand version only.
    • Some people might get frequent cold-like symptoms.
    • Rare but serious side effects include pancreatitis and severe joint pain.
    Tips from our pharmacists for people taking the medication
    NesinaJanuvia
    • Can cause headache and cold-like symptoms.
    • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
    • Can be expensive depending on insurance coverage.
    • Check your blood sugar regularly.
    • Take once a day in the morning with or without food.
    • Can cause headache and cold-like symptoms.
    • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
    • Tell your doctor right away if you are experiencing severe joint pain.
    • Check your blood sugar regularly to check for low blood sugar.
    Learn more
    More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Nesina (alogliptin)?
    Worth itNot sureNot worth it
    More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Januvia (sitagliptin)?
    Worth itNot sureNot worth it