Compare Nesina vs. metformin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers your blood sugar.

alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.

Lowers blood sugar.

Glucophage (metformin) is the first choice medicine to control your blood sugar and lower the risk of death from diabetes, although a few people may not tolerate the stomach side effects.

3.7/ 5 average rating with 938 reviewsformetformin
Upsides
  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • Rarely causes low blood sugar.
  • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
  • Improves sugar control and lowers A1c levels as much as 2%.
  • One of the few diabetes medicines that lowers the risk of death from diabetes-related complications.
  • Doesn't cause weight gain.
  • Rarely causes low blood sugar.
Downsides
  • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
  • Likely expensive since there's no generic version available.
  • Some people might get frequent throat infections or nasal congestion.
  • Often causes stomach upset, like diarrhea, nausea, gas, or stomach cramping.
  • Usually not a good choice for people with kidney problems. Your doctor will tell you if Glucophage (metformin) is right for you to take.
  • Excessive or chronic alcohol use can increase the risk of a dangerous side effect.
Used for
  • Diabetes mellitus type 2
Dosage forms
  • Pill
  • Pill
  • Extended release pill
  • Liquid
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
Not enough review data.Leave a review
938 reviews so far
65%
saidit'sworth it
46%
saiditworked well
16%
saidit'sa big hassle

Have you used Glucophage (metformin)?

Leave a review
Side effects
The Nesina (Alogliptin) FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Diarrhea
    53%
  • Nausea/vomiting
    26%
  • Gas
    12%
  • Weakness
    9%
  • Indigestion
    7%
  • Stomach pain
    6%
  • Headache
    6%
See more detailed side effects
Risks and risk factors
  • Pancreatitis
  • Liver damage
See more detailed risks and warnings
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
See more detailed risks and warnings