Compare Neupogen vs. Procrit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neupogen (filgrastim)

Prescription only

Procrit (epoetin alfa)

Prescription only
Prevents infection during chemotherapy.

Neupogen (filgrastim) can lower your risk of infection during chemotherapy, but it can cause a significant amount of bone pain.

Treats low red blood cell count.

Procrit (epoetin alfa) is effective at treating low red blood cell count, but it might cause tumor growth and increased risk of blood clots.

Upsides
  • Neupogen (filgrastim) is effective at preventing infection during chemotherapy.
  • There are no dosage adjustments if you have kidney and liver problems.
  • Procrit (epoetin alfa) is effective at treating anemia if you have kidney problems or cancer.
  • Procrit (epoetin alfa) doesn't have to be injected every day.
  • There are no dosage adjustments if you have kidney and liver problems.
Downsides
  • If you decide not to self-inject and don't have someone to do it for you, you'll need to have your doctor or trained medical staff give you each dose of Neupogen (filgrastim).
  • You'll need to properly dispose of the needle and syringe in a special (FDA-approved) sharps container.
  • Neupogen (filgrastim) is not available as a generic, and is expensive.
  • Neupogen (filgrastim) is injected every day, whereas Neulasta is injected every 10-14 days.
  • Procrit (epoetin alfa) is only available as an injectable.
  • When using Procrit (epoetin alfa), your blood has to be constantly monitored.
  • Procrit (epoetin alfa) is not available as a generic and is expensive.
  • You must have normal iron levels before starting Procrit (epoetin alfa).
  • If you have high blood pressure, Procrit (epoetin alfa) may not be the right medication for you.
Used for
  • Severe chronic neutropenia
  • Febrile neutropenia prophylaxis in myelosuppressive chemotherapy recipients with nonmyeloid malignancies
  • Febrile neutropenia prophylaxis in acute myeloid leukemia (AML) following induction or consolidation chemotherapy
  • Bone marrow transplantation
  • Hematopoietic radiation injury syndrome
  • Peripheral blood progenitor cell collection and therapy
  • Anemia due to chemotherapy in cancer patients
  • Anemia due to chronic kidney disease
  • Anemia due to zidovudine in HIV-infected patients
  • Reduction of Allogeneic Red Blood Cell Transfusions in Patients Undergoing Elective, Noncardiac, Nonvascular Surgery
Dosage forms
  • Injection
  • Injection
Price
Lowest price
$2007.82
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
16possible side effects
  • Fever
    48%
  • Nausea
    43%
  • Decreased platelets
    38%
  • Fatigue
    20%
  • Back pain
    15%
  • Dizziness
    14%
  • Cough
    14%
  • Rash
    14%
  • Chest pain
    13%
  • Shortness of breath
    13%
  • Pain
    12%
  • Bone pain
    11%
  • Joint pain
    9%
  • Pain in extremity
    7%
  • Increased blood lactate dehydrogenase
    6%
  • Increase blood alkaline phosphatase
    6%
See more detailed side effects
26possible side effects
  • Fever
    42%
  • Nausea
    35%
  • High blood pressure
    28%
  • Cough
    26%
  • Vomiting
    20%
  • Rash
    19%
  • Joint pain
    16%
  • Dizziness
    10%
  • Muscle pain
    10%
  • Swelling in the mouth
    10%
  • Decreased weight
    9%
  • Medical device malfunction (artificial kidney clotting during dialysis)
    8%
  • Blockage of blood vessel
    8%
  • Decrease in white blood cells
    8%
  • Muscle spasm
    7%
  • Upper respiratory tract infection
    7%
  • Injection site irritation
    7%
  • Bone pain
    7%
  • High blood sugar
    6%
  • Difficulty sleeping
    6%
  • Headache
    5%
  • Depression
    5%
  • Difficulty swallowing
    5%
  • Low potassium
    5%
  • Blood clot
    5%
  • Hives
    3%
See more detailed side effects
Risks and risk factors
  • Serious allergic reactions
    • Allergy to Neupogen (filgrastim)
  • Respiratory problems
  • Spleen problems
  • Blood problems
    • Sickle cell disease
    • Sickle cell crisis while taking filgrastim
  • Malignancy
    • History of myeloid cancers or myelodysplastic conditions
  • Capillary leak syndrome (CLS)
See more detailed risks and warnings
  • Increased risk of death and other serious events
    • History of heart disease
    • Uncontrolled hypertension
    • High red blood cell count
  • Tumor growth
  • Risk of blood clots when recovering from surgery
  • High blood pressure
  • Seizures
    • History of seizures.
  • Lack or loss of hemoglobin response to Procrit (epoetin alfa)
  • Serious allergic reactions
See more detailed risks and warnings