Compare Neurontin vs. Celexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neurontin
(Gabapentin)

Celexa
(Citalopram)

Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.542087542087542Neurontin
Reviews for Neurontin (Gabapentin)
57%
of people (All ages) say Neurontin (Gabapentin) is worth it
39%
say it works well
19%
say it's a big hassle
594 reviews
Have you used Neurontin (Gabapentin)?
Worth itNot sureNot worth it
Reviews for Celexa (Citalopram)
60%
+3% vs. Neurontin (Gabapentin)
50%
+11% vs. Neurontin (Gabapentin)
15%
+4% vs. Neurontin (Gabapentin)
458 reviews
Have you used Celexa (Citalopram)?
Worth itNot sureNot worth it
Side effects
NeurontinCelexa
  • Dizziness 21%
  • Drowsiness 16%
  • Lack of muscle coordination 7%
  • Leg or ankle swelling 6%
  • Fatigue 6%
  • Hostility 5%
  • Involuntary eye movement 4%
  • Double vision 4%
  • Tremor 4%
  • Dry mouth 4%
More Neurontin side effects »
  • Drowsiness 8%
  • Nausea 7%
  • Dry mouth 6%
  • Abnormal ejaculation 5%
  • Ejaculation disorder 5%
  • Diarrhea 3%
  • Tremor 2%
  • Sweating increased 2%
  • Fatigue 2%
  • Loss of appetite 2%
More Celexa side effects »
How it works
NeurontinCelexa
Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
NeurontinCelexa
Anticonvulsant
GABA analog
Prescription only
Antidepressant
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Available as
NeurontinCelexa
  • Pill
  • Oral solution
  • Pill
  • Oral solution
Used for (click to learn more)
NeurontinCelexa
Risk factors for serious side effects
NeurontinCelexa
    • Children ages 3 to 12
      • Taking with alcohol or drugs
      • Stopping Neurontin (Gabapentin) suddenly
      Detailed Neurontin (Gabapentin) risks & warnings »
      • Age 24 years or younger
      • Using other medications that affect serotonin
      • History of bipolar disorder
      • At risk for bipolar disorder
      • Stopping Celexa (Citalopram) suddenly
      • Higher dose
      • History of heart problems
      • History of liver problems
      • Older age
      • Taking other blood-thinning drugs
        Detailed Celexa (Citalopram) risks & warnings »
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Food
        NeurontinCelexa
        • Take the extended-release tablet with food.
        • Take with food to avoid upset stomach.
        Kidneys and liver
        NeurontinCelexa
        No kidneys and liver related info.
        • Not a good option for you if you have heart or liver problems.
        Pain
        NeurontinCelexa
        • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
        No pain related info.
        Sex
        NeurontinCelexa
        No sex related info.
        • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
        Sleep
        NeurontinCelexa
        • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
        No sleep related info.
        Weight
        NeurontinCelexa
        No weight related info.
        • Can cause minor weight gain (1 to 5 pounds).
        Upsides and benefits
        NeurontinCelexa
        • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
        • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
        • It's available as a generic, so it's less expensive than similar medications.
        • Effective at relieving depression and anxiety symptoms.
        • Causes less sleepiness compared to other antidepressants.
        • Six out of ten people who use an antidepressant for the first time find that it works for them.
        Downsides and risks
        NeurontinCelexa
        • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
        • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
        • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
        • Can cause minor weight gain (1 to 5 pounds).
        • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
        • Not a good option for you if you have heart or liver problems.
        • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
        • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
        Tips from our pharmacists for people taking the medication
        NeurontinCelexa
        • Side effects are common, but usually manageable.
        • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
        • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
        • Take the extended-release tablet with food.
        • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
        • Take with food to avoid upset stomach.
        • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
        • Stop taking it slowly to avoid getting withdrawal symptoms.
        • Tell your doctor if you notice sudden mood changes or unusual thoughts.
        Learn more
        More about NeurontinSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Neurontin (Gabapentin)?
        Worth itNot sureNot worth it
        More about CelexaSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Celexa (Citalopram)?
        Worth itNot sureNot worth it