Compare Neurontin vs. Geodon

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neurontin
(gabapentin)

Geodon
(ziprasidone)

Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.Helps control your thoughts and mood. Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.56Neurontin
Reviews for Neurontin
57%
of people (All ages) say Neurontin is worth it
40%
say it works well
19%
say it's a big hassle
620 reviews
Have you used Neurontin (gabapentin)?
Worth itNot sureNot worth it
Reviews for Geodon
43%
+14% better vs. Neurontin
43%
-3% worse vs. Neurontin
30%
+11% better vs. Neurontin
Have you used Geodon (ziprasidone)?
Worth itNot sureNot worth it
Side effects
NeurontinGeodon
  • Dizziness 21%
  • Somnolence 16%
  • Peripheral edema 6%
  • Asthenia 1%
  • Diarrhea 2%
  • Infection 2%
  • Dry mouth 3%
  • Constipation 2%
  • Accidental injury 2%
  • Vomiting 2%
More Neurontin side effects »
  • Extrapyramidal Symptoms 6%
  • Somnolence 7%
  • Nausea 3%
  • Constipation 1%
  • Respiratory Tract Infection 5%
  • Dizziness 2%
  • Dyspepsia 1%
  • Akathisia 1%
  • Asthenia 2%
  • Diarrhea 1%
More Geodon side effects »
How it works
NeurontinGeodon
Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.Geodon (Ziprasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar disorder by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.
Type of medication
NeurontinGeodon
Prescription onlyPrescription only
Available as
NeurontinGeodon
  • Pill
  • Oral solution
  • Pill
  • Injection
Used for
NeurontinGeodon
Risk factors for serious side effects
NeurontinGeodon
  • Children ages 3 to 12
  • Taking with alcohol or drugs
  • Stopping Neurontin (Gabapentin) suddenly
Detailed Neurontin (gabapentin) risks & warnings »
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • Low potassium
  • Low magnesium
Detailed Geodon (ziprasidone) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
NeurontinGeodon
  • Take the extended-release tablet with food.
No food related info.
Pain
NeurontinGeodon
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
No pain related info.
Sleep
NeurontinGeodon
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
Weight
NeurontinGeodon
No weight related info.
  • It causes slightly less weight gain than similar medicines.
Upsides and benefits
NeurontinGeodon
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
Downsides and risks
NeurontinGeodon
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
  • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
Tips from our pharmacists for people taking the medication
NeurontinGeodon
  • Side effects are common, but usually manageable.
  • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
  • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
  • Take the extended-release tablet with food.
  • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
  • It usually takes 4 to 6 weeks to see the full effects, so hang in there and wait until it works to figure out the right dose for you.
  • Take Geodon (Ziprasidone) twice a day, preferably with food.
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
  • Geodon (Ziprasidone) can cause heart problems, so call your doctor right away if you faint or feel a change in your heartbeat.
  • Let your doctor know if you're taking a diuretic (water pill) or have a condition like chronic diarrhea that'll lower the amount of potassium or magnesium in your blood.
Learn more
More about NeurontinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Neurontin (gabapentin)?
Worth itNot sureNot worth it
More about GeodonSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Geodon (ziprasidone)?
Worth itNot sureNot worth it