Compare Neurontin vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neurontin (gabapentin)

Prescription only

Oleptro (Trazodone)

Prescription only
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

4.6/ 7 average rating with 620 reviewsforNeurontin
Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

4.9/ 7 average rating with 59 reviewsforOleptro
Upsides
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Extended release
  • Pill
  • Extended release
Price
Lowest price near you
$12.05
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Lowest price near you
$4
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Reviews
620 
57%
think this treatment is worth it
40%
think this treatment works well
19%
think this treatment is a hassle

Have you used Neurontin (gabapentin)?

Leave a review
59 
73%
think this treatment is worth it
49%
think this treatment works well
24%
think this treatment is a hassle

Have you used Oleptro (Trazodone)?

Leave a review
Side effects
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
See more detailed side effects
Risks and warnings
  • Neurologic and psychiatric side effects (children)

    Children ages 3 to 12

  • Driving impairment

    Taking Neurontin (gabapentin) with alcohol

    ...and 1 more risk factors

  • Withdrawal seizures

    Stopping Neurontin (gabapentin) suddenly

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Seizures

    History of seizures

    ...and 4 more risk factors

  • Low blood pressure

    Age 65 years or older

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings