Compare Neurontin vs. Propranolol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neurontin (gabapentin)

Prescription only

Inderal (Propranolol)

Prescription only
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

4.6/ 7 average rating with 620 reviewsforNeurontin
Lowers blood pressure and controls heart rate.

Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.

5.4/ 7 average rating with 61 reviewsforPropranolol
Upsides
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
  • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
Downsides
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Extended release
  • Pill
  • Extended release
  • Liquid
Price
Lowest price near you
$12.05
Find instant savings
Lowest price near you
$9.99
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
620 
57%
think this treatment is worth it
40%
think this treatment works well
19%
think this treatment is a hassle

Have you used Neurontin (gabapentin)?

Leave a review
61 
66%
think this treatment is worth it
62%
think this treatment works well
15%
think this treatment is a hassle

Have you used Inderal (Propranolol)?

Leave a review
Side effects
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
3possible side effects
  • Dizziness
    7%
  • Fatigue
    5%
  • Constipation
    3%
See more detailed side effects
Risks and warnings
  • Neurologic and psychiatric side effects (children)

    Children ages 3 to 12

  • Driving impairment

    Taking Neurontin (gabapentin) with alcohol

    ...and 1 more risk factors

  • Withdrawal seizures

    Stopping Neurontin (gabapentin) suddenly

See more detailed risks and warnings
  • Increased chest pain or risk of heart attack

    Suddenly stopping Inderal (Propranolol)

  • Increased risks during surgery

    Major surgery requiring anesthesia

  • Masked symptoms of low blood sugar

    Diabetes

  • Low blood pressure

    Concurrent use of non-dihydropyridine calcium channel blockers, digoxin or clonidine

See more detailed risks and warnings