Compare Neurontin vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Neurontin (gabapentin)

Prescription only

Remeron (mirtazapine)

Prescription only
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

3.4/ 5 average rating with 620 reviewsforNeurontin
Improves mood.

Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.

3.3/ 5 average rating with 152 reviewsforRemeron
Upsides
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
Downsides
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Extended release
  • Pill
  • Dissolving tablet
Price
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Reviews
620 reviews so far
57%
saidit'sworth it
40%
saiditworked well
19%
saidit'sa big hassle

Have you used Neurontin (gabapentin)?

Leave a review
152 reviews so far
45%
saidit'sworth it
39%
saiditworked well
26%
saidit'sa big hassle

Have you used Remeron (mirtazapine)?

Leave a review
Side effects
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
The Remeron (mirtazapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
  • Neurologic and psychiatric side effects (children)
    • Children ages 3 to 12
  • Serious allergic reaction and multiple organ problems
  • Driving impairment
    • Taking Neurontin (gabapentin) with alcohol
    • Taking other medicines that cause dizziness and/or drowsiness
  • Withdrawal seizures
    • Stopping Neurontin (gabapentin) suddenly
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Heart problems
    • History of heart problems
    • History of liver problems
    • Higher dose
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Weight gain
  • Blood disorders
See more detailed risks and warnings