Compare Niaspan vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Niaspan (Niacin)

Prescription only
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

4.2/ 7 average rating with 380 reviewsforNiaspan
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

3.8/ 7 average rating with 68 reviewsforTrilipix
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
Price
Lowest price near you
$67.88
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Lowest price near you
$64.75
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Reviews
380 
43%
think this treatment is worth it
31%
think this treatment works well
19%
think this treatment is a hassle

Have you used Niaspan (Niacin)?

Leave a review
68 
50%
think this treatment is worth it
22%
think this treatment works well
25%
think this treatment is a hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
Side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Muscle pain

    Taking Niaspan (Niacin) with statins

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • High blood sugar

    Diabetes

  • Low platelets

    Taking Niaspan (Niacin) with anticoagulants

  • Gout

    Gout

See more detailed risks and warnings
  • Muscle pain

    Taking Trilipix (Fenofibric Acid) with statins

  • Liver damage

    Past history of liver disease

  • Increased bleeding risk

    Taking Trilipix (Fenofibric Acid) with anticoagulants

See more detailed risks and warnings