Compare Niaspan vs. Vytorin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Niaspan (Niacin)

Prescription only
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

3.2/ 5 average rating with 380 reviewsforNiaspan
Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

3.3/ 5 average rating with 99 reviewsforVytorin
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
Downsides
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
No pricing information available
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Reviews
380 reviews so far
43%
saidit'sworth it
31%
saiditworked well
19%
saidit'sa big hassle

Have you used Niaspan (Niacin)?

Leave a review
99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
Side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Taking Niaspan (Niacin) with statins
  • Liver damage
    • Heavy alcohol use
    • Past history of liver disease
  • High blood sugar
    • Diabetes
  • Low platelets
    • Taking Niaspan (Niacin) with anticoagulants
  • Gout
    • Gout
See more detailed risks and warnings
  • Muscle pain
    • Asian patients taking high-dose niacin
  • Liver damage
    • Past history of liver disease
    • heavy alcohol use
  • High blood sugar
    • Diabetes
  • Increased risk for colds and flu
  • Skin reactions
  • Harm to fetus
    • Pregnancy
See more detailed risks and warnings