Compare Nifedipine vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Procardia
(Nifedipine)

Coreg
(Carvedilol)

Lowers blood pressure and controls heart rate. Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.6Nifedipine
Reviews for Procardia (Nifedipine)
40%
of people say Procardia (Nifedipine) is worth it
28%
say it works well
48%
say it's a big hassle
Reviews for Coreg (Carvedilol)
54%
+14% vs. Procardia (Nifedipine)
46%
+18% vs. Procardia (Nifedipine)
18%
+30% vs. Procardia (Nifedipine)
Side effects
NifedipineCoreg
  • Leg or ankle swelling 19%
  • Flushing 17%
  • Dizziness, lightheadedness, giddiness 12%
  • Muscle cramps, tremor 5%
  • Nervousness, mood changes 3%
  • Headache 3%
  • Dyspnea, cough, wheezing 3%
  • Nausea, heartburn 3%
  • Heart pounding or racing sensation 2%
  • Dizziness 2%
More Nifedipine side effects »
  • Dizziness 13%
  • Abnormally slow heartbeat 7%
  • Low blood pressure 6%
  • Diarrhea 6%
  • High blood sugar 4%
  • Nausea 4%
  • Vision abnormal 3%
  • Fainting 3%
  • Muscle weakness 2%
  • Edema dependent 2%
More Coreg side effects »
How it works
NifedipineCoreg
Nifedipine is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
NifedipineCoreg
Antihypertensive
Calcium channel blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
NifedipineCoreg
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
NifedipineCoreg
Risk factors for serious side effects
NifedipineCoreg
  • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
  • History of intestinal surgery
  • Taking beta-blockers
  • Severe coronary artery disease.
  • History of cirrhosis
    • History of tight aortic stenosis
    • Taking beta-blockers
    • Obstructive coronary artery disease
    Detailed Procardia (Nifedipine) risks & warnings »
    • Abrupt discontinuation of Coreg (Carvedilol)
        • Congestive heart failure
        • Increasing the dose of Coreg (Carvedilol)
        • Diabetes
        • Major surgery requiring anesthesia
          Detailed Coreg (Carvedilol) risks & warnings »
          Pregnancy category
          NifedipineCoreg
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.
          • You have to take Carvedilol with food.
          • Take it with food.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          No specific weight-related info.
          • You may notice worsening symptoms of heart failure if your prescriber decides to increase your dosage of Coreg (Carvedilol). Tell your doctor if you noticed increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as they may make changes to your medications for heart failure.
          Upsides and benefits
          NifedipineCoreg
          • A first-choice blood pressure treatment for many people.
          • Calcium channel blockers work especially well for African Americans to lower blood pressure.
          • You can take it alone or with other medicines to help lower blood pressure.
          • Lowers the risk of heart attack and stroke.
          • Prevents heart-related chest pain (angina) if you take it regularly.
          • Treats certain abnormal heart rhythms.
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          Downsides and risks
          NifedipineCoreg
          • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
          • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
          • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
          • You have to take Carvedilol with food.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          Tips from our pharmacists for people taking the medication
          NifedipineCoreg
          • Can cause dizziness or headaches in the first few days.
          • Can cause face flushing and ankle or foot swelling.
          • Avoid grapefruit while taking this medicine.
          • Your doctor might do routine blood tests to check your liver function.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Take it with food.
          • Can cause dizziness in the first few days.
          • Can cause fatigue and erectile dysfunction.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          Learn more
          More about NifedipineSide effectsReviews & ratingsAlternativesFDA package insert
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert