Compare Nifedipine vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Procardia (Nifedipine)

Prescription only

Plendil (felodipine)

Prescription only
Lowers blood pressure and controls heart rate.

Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.

2.8/ 5 average rating with 26 reviewsforNifedipine
Lowers blood pressure.

Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
  • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release
Price
No pricing information available
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Reviews
26 reviews so far
42%
saidit'sworth it
31%
saiditworked well
46%
saidit'sa big hassle

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Side effects
11possible side effects
  • Dizziness, lightheadedness, giddiness
    27%
  • Flushing
    25%
  • Headache
    23%
  • Weakness
    12%
  • Nausea, heartburn
    11%
  • Muscle cramps, tremor
    8%
  • Peripheral edema
    7%
  • Nervousness, mood changes
    7%
  • Palpitation
    7%
  • Dyspnea, cough, wheezing
    6%
  • Nasal congestion, sore throat
    6%
See more detailed side effects
8possible side effects
  • Headache
    10%
  • Swelling
    9%
  • Flushing
    5%
  • Racing heart beat
    4%
  • Weakness
    3%
  • Dizziness
    3%
  • Nausea
    2%
  • Colds or flu
    2%
See more detailed side effects
Risks and risk factors
  • Intestinal blockage
    • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
    • History of intestinal surgery
  • Chest pain
    • Taking beta-blockers
    • Severe coronary artery disease.
  • Liver damage/jaundice
    • History of cirrhosis
  • Low blood pressure
  • Congestive heart failure
    • History of tight aortic stenosis
    • Taking beta-blockers
  • Heart attack or increased chest pain
    • Obstructive coronary artery disease
See more detailed risks and warnings
  • Low blood pressure
    • Over age 65
  • Heart failure
    • Taking in combination with a beta-blocker
  • Special dosing requirements
    • Liver disease
    • Over age 65
  • Swelling in arms and legs
    • History of heart failure
    • History of kidney disease
See more detailed risks and warnings