Compare Nifedipine vs. Plendil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Procardia
(Nifedipine)

Plendil
(Felodipine)

Lowers blood pressure and controls heart rate. Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.6Nifedipine
Reviews for Procardia (Nifedipine)
40%
of people say Procardia (Nifedipine) is worth it
28%
say it works well
48%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
NifedipinePlendil
  • Leg or ankle swelling 19%
  • Flushing 17%
  • Dizziness, lightheadedness, giddiness 12%
  • Muscle cramps, tremor 5%
  • Nervousness, mood changes 3%
  • Headache 3%
  • Dyspnea, cough, wheezing 3%
  • Nausea, heartburn 3%
  • Heart pounding or racing sensation 2%
  • Dizziness 2%
More Nifedipine side effects »

We haven’t found good data for Plendil side effects.

FDA side effect reports for Plendil »
How it works
NifedipinePlendil
Nifedipine is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coming soon.
Type of medication
NifedipinePlendil
Antihypertensive
Calcium channel blocker
Prescription only
Coming soon.
Available as
NifedipinePlendil
  • Pill
  • Extended release
  • Extended release
Used for (click to learn more)
NifedipinePlendil
  • Hypertension
Risk factors for serious side effects
NifedipinePlendil
  • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
  • History of intestinal surgery
  • Taking beta-blockers
  • Severe coronary artery disease.
  • History of cirrhosis
    • History of tight aortic stenosis
    • Taking beta-blockers
    • Obstructive coronary artery disease
    Detailed Procardia (Nifedipine) risks & warnings »
    Coming soon.
    Pregnancy category
    NifedipinePlendil
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    NifedipinePlendil
    • A first-choice blood pressure treatment for many people.
    • Calcium channel blockers work especially well for African Americans to lower blood pressure.
    • You can take it alone or with other medicines to help lower blood pressure.
    • Lowers the risk of heart attack and stroke.
    • Prevents heart-related chest pain (angina) if you take it regularly.
    • Treats certain abnormal heart rhythms.
    Coming soon.
    Downsides and risks
    NifedipinePlendil
    • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
    • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
    • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    NifedipinePlendil
    • Can cause dizziness or headaches in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Can cause face flushing and ankle or foot swelling.
    • Avoid grapefruit while taking this medicine.
    • Your doctor might do routine blood tests to check your liver function.
    Coming soon.
    Learn more
    More about NifedipineSide effectsReviews & ratingsAlternativesFDA package insert
    More about PlendilSide effectsReviews & ratingsFDA package insert