Compare Norco vs. Acetaminophen With Codeine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Norco (hydrocodone / acetaminophen)

Prescription only
Treats moderate to moderately severe pain.

Norco (hydrocodone / acetaminophen) is a good option to treat pain when over-the-counter medicines haven't worked, but it can lead to dependence and tolerance if taken for a long time.

5.0/ 7 average rating with 1194 reviewsforNorco
Treats mild to moderate pain.

Tylenol #3 (Acetaminophen / Codeine) is a good option to treat pain and cough as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.

5.0/ 7 average rating with 581 reviewsforAcetaminophen With Codeine
Upsides
  • Norco (hydrocodone / acetaminophen) has two medicines to treat moderate to moderately severe pain. The combination is more effective than either drug alone.
  • Norco (hydrocodone / acetaminophen) is more potent than many over-the-counter options.
  • You can take this with or without food.
  • This medicine also comes as a liquid if you have trouble swallowing.
  • Norco (hydrocodone / acetaminophen) is available as a generic.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relieve for mild to moderate pain to improve quality of life.
  • Good for as-needed pain and control.
  • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
Downsides
  • Constipation, dizziness, drowsiness, and nausea can commonly occur.
  • Since Norco (hydrocodone / acetaminophen) is a controlled medication, it cannot be refilled or transferred to another pharmacy.
  • Long-term use can cause dependence and tolerance.
  • Too much Norco (hydrocodone / acetaminophen) can damage the liver.
  • Not effective in treating all kinds of pain.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Acetaminophen with codeine if you need.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • The non-opioid part of Acetaminophen with codeine, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
Used for
  • Moderate to severe pain
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
Price
Lowest price near you
$196.12
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$6.2
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Reviews
1194 
67%
think this treatment is worth it
44%
think this treatment works well
13%
think this treatment is a hassle

Have you used Norco (hydrocodone / acetaminophen)?

Leave a review
581 
69%
think this treatment is worth it
41%
think this treatment works well
9%
think this treatment is a hassle

Have you used Tylenol #3 (Acetaminophen / Codeine)?

Leave a review
Side effects
The Norco (hydrocodone / acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
The Tylenol #3 (Acetaminophen / Codeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Liver failure

    Current liver disease

    ...and 2 more risk factors

  • Slowed breathing

    Age 65 or greater

    ...and 3 more risk factors

  • Severe allergic reactions

    Taking more than the prescribed dose

    ...and 3 more risk factors

  • Tolerance, dependence, and addiction

    Taking more than the prescribed dose

    ...and 3 more risk factors

  • Constipation

    Age 65 or greater

    ...and 2 more risk factors

  • Confusion and drowsiness

    Drinking alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
No information currently available