Compare Norco vs. Acetaminophen With Codeine

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Norco
(Hydrocodone / Acetaminophen)

Tylenol #3
(Acetaminophen / Codeine)

Treats moderate to severe pain. Norco (Hydrocodone / Acetaminophen) is a good option to treat pain as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.Treats mild to moderate pain. Tylenol #3 (Acetaminophen / Codeine) is a good option to treat pain and cough as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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Reviews & ratings
Filter group. All currently selected
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5.03Norco
Reviews for Norco (Hydrocodone / Acetaminophen)
67%
of people (All ages) say Norco (Hydrocodone / Acetaminophen) is worth it
44%
say it works well
13%
say it's a big hassle
1194 reviews
Have you used Norco (Hydrocodone / Acetaminophen)?
Worth itNot sureNot worth it
Reviews for Tylenol #3 (Acetaminophen / Codeine)
69%
+2% vs. Norco (Hydrocodone / Acetaminophen)
41%
3% vs. Norco (Hydrocodone / Acetaminophen)
9%
+4% vs. Norco (Hydrocodone / Acetaminophen)
581 reviews
Have you used Tylenol #3 (Acetaminophen / Codeine)?
Worth itNot sureNot worth it
Side effects
NorcoAcetaminophen With Codeine

The Norco FDA package insert doesn’t have numbers about how common side effects are.

More about Norco side effects »

The Acetaminophen With Codeine FDA package insert doesn’t have numbers about how common side effects are.

More about Acetaminophen With Codeine side effects »
How it works
NorcoAcetaminophen With Codeine
Norco (Hydrocodone / Acetaminophen) is a combination pain medicine. Hydrocodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.Tylenol #3 (Acetaminophen / Codeine) is a combination pain medicine. Codeine is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.
Type of medication
NorcoAcetaminophen With Codeine
Pain reliever
Opioid
Acetaminophen (APAP)
Prescription only
Pain reliever
Acetaminophen (APAP)
Opioid
Prescription only
Available as
NorcoAcetaminophen With Codeine
  • Pill
  • Oral solution
  • Pill
  • Liquid
Used for (click to learn more)
NorcoAcetaminophen With Codeine
Risk factors for serious side effects
NorcoAcetaminophen With Codeine
  • Current liver disease
  • Taking with alcohol
  • Taking other medicines with acetaminophen
  • Age 65 or greater
  • Higher dose
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
NorcoAcetaminophen With Codeine
  • Avoid alcohol.
  • Avoid alcohol.
Food
NorcoAcetaminophen With Codeine
  • Take it with food to lower the chance of an upset stomach.
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
NorcoAcetaminophen With Codeine
  • Don't take more than instructed to prevent liver damage.
  • The acetaminophen component in Norco (Hydrocodone / Acetaminophen) can hurt your liver. Using more than 4000 mg of the acetaminophen (or 12 tablets of Norco (Hydrocodone / Acetaminophen) can cause serious harm to your liver. You may develop life-threatening liver problems that need a liver transplant. Don't take more than your doctor prescribes, and avoid other medicines that have acetaminophen when using Norco (Hydrocodone / Acetaminophen).
  • Don't take more than instructed to prevent liver damage.
Pain
NorcoAcetaminophen With Codeine
  • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
  • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Good for as-needed pain and control.
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
Sleep
NorcoAcetaminophen With Codeine
  • Can help you fall asleep easier.
  • Dizziness and drowsiness is common.
  • Can help you fall asleep easier.
  • Dizziness and drowsiness is common, but your body may adjust.
Upsides and benefits
NorcoAcetaminophen With Codeine
  • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relief for moderate to severe pain to improve quality of life.
  • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
  • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relieve for mild to moderate pain to improve quality of life.
  • Good for as-needed pain and control.
  • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
Downsides and risks
NorcoAcetaminophen With Codeine
  • Dizziness and drowsiness is common.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Norco if you need.
  • The non-opioid part of Norco, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Acetaminophen with codeine if you need.
  • The non-opioid part of Acetaminophen with codeine, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
Tips from our pharmacists for people taking the medication
NorcoAcetaminophen With Codeine
  • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
  • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
  • Use it for the shortest time and at the lowest dose possible, to lower your chance of becoming addicted.
  • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
  • Take it with food to lower the chance of an upset stomach.
  • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
  • Don't take more than instructed to prevent liver damage.
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Starts working in 30 minutes.
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
  • Can make you dizzy or drowsy.
  • Avoid activities need you to be fully alert until you know how it affects you.
  • Use it for the shortest time possible, and at the lowest dose possible, to lower your chance of becoming addicted.
  • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
  • Take it with food to lower the chance of an upset stomach.
  • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
  • Don't take more than instructed to prevent liver damage.
Learn more
More about NorcoSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Norco (Hydrocodone / Acetaminophen)?
Worth itNot sureNot worth it
More about Acetaminophen With CodeineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tylenol #3 (Acetaminophen / Codeine)?
Worth itNot sureNot worth it