Compare Norco vs. Percocet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Norco
(Hydrocodone / Acetaminophen)

Percocet
(Oxycodone / Acetaminophen)

Treats moderate to severe pain. Norco (Hydrocodone / Acetaminophen) is a good option to treat pain as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.Treats moderate to severe pain. Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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Reviews & ratings
Button Group. All currently active
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5.027824620573356Norco
Reviews for Norco (Hydrocodone / Acetaminophen)
67%
of people say Norco (Hydrocodone / Acetaminophen) is worth it
44%
say it works well
13%
say it's a big hassle
Reviews for Percocet (Oxycodone / Acetaminophen)
69%
+2% vs. Norco (Hydrocodone / Acetaminophen)
49%
+5% vs. Norco (Hydrocodone / Acetaminophen)
15%
2% vs. Norco (Hydrocodone / Acetaminophen)
Side effects
NorcoPercocet

The Norco FDA package insert doesn’t have numbers about how common side effects are.

More about Norco side effects »

The Percocet FDA package insert doesn’t have numbers about how common side effects are.

More about Percocet side effects »
How it works
NorcoPercocet
Norco (Hydrocodone / Acetaminophen) is a combination pain medicine. Hydrocodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.Percocet (Oxycodone / Acetaminophen) is a combination pain medicine. Oxycodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.
Type of medication
NorcoPercocet
Pain reliever
Opioid
Acetaminophen (APAP)
Prescription only
Pain reliever
Opioid
Acetaminophen (APAP)
Prescription only
Available as
NorcoPercocet
  • Pill
  • Oral solution
  • Pill
  • Oral solution
Used for (click to learn more)
NorcoPercocet
Risk factors for serious side effects
NorcoPercocet
  • Current liver disease
  • Taking with alcohol
  • Taking other medicines with acetaminophen
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
    • Long-term use of opioids in mother
    • Breastfeeding while taking Norco (Hydrocodone / Acetaminophen)
    • Taking more than the prescribed dose
    • Long-term use
    • History of drug abuse
    Detailed Norco (Hydrocodone / Acetaminophen) risks & warnings »
    • Current liver disease
    • Taking with alcohol
    • Taking other medicines with acetaminophen
    • Age 65 or greater
    • Higher dose
    • People with not enough thyroid hormones
    • History of lung problems
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
    • Taking more than the prescribed dose
    • Long-term use
    • History of drug abuse
    • Long-term use of opioids in mother
    • Breastfeeding while taking Percocet (Oxycodone / Acetaminophen)
    • Children age 18 and younger
    • Taking more than prescribed dose
    • Mixing with alcohol or drugs that interact with Percocet (Oxycodone / Acetaminophen)
      • Age 65 years or older
      • Circulation problems
      Detailed Percocet (Oxycodone / Acetaminophen) risks & warnings »
      Pregnancy category
      NorcoPercocet
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      • Avoid alcohol.
      • Avoid alcohol.
      • Even 1 dose of an extended-release tablet can be too much for a child so store out of reach from children. In adults, raising the dose too quickly, high doses or mixing with alcohol or drugs that interact causes overdose and death. If you suspect a child has taken Percocet (Oxycodone / Acetaminophen), or an adult has taken too much, watch them for decreased activity, extreme tiredness small pupils, and lips and fingers turning blue from low oxygen. Call 911 or go to a hospital immediately. Doctors can give a medicine that reverses the effects of Percocet (Oxycodone / Acetaminophen).
      Food
      • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
      • Take it with food to lower the chance of an upset stomach.
      • Take it with food to lower the chance of an upset stomach.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      • Dizziness and drowsiness is common.
      • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
      • Dizziness and drowsiness is common, but your body may adjust.
      • Can make you dizzy or drowsy.
      Weight
      • Hydrocodone, one of the medications in Norco (Hydrocodone / Acetaminophen) passes into breast milk. Women with a history of long-term opioid use increase the risk of neonatal withdrawal syndrome. Symptoms in the newborn include irritability, vomiting, diarrhea, tremor and lack of weight gain. Opioid withdrawal in infants is a life-threatening emergency and needs medical help right away.
      • Oxycodone, one of the medications in Percocet (Oxycodone / Acetaminophen) passes into breast milk. Women with a history of long-term opioid use increase the risk of neonatal withdrawal syndrome. Symptoms in the newborn include irritability, vomiting, diarrhea, tremor and lack of weight gain. Opioid withdrawal in infants can be a life-threatening emergency and needs immediate medical care.
      Upsides and benefits
      NorcoPercocet
      • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
      • Provides quick relief for moderate to severe pain to improve quality of life.
      • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
      • Lower rates of misuse compared to pure opioid medicines.
      • Can help you fall asleep easier.
      • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • Generally considered stronger than Norco or other combination pain medicine for treating pain.
      • Provides quick relief for moderate to severe pain to improve quality of life.
      • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
      • Lower rates of misuse compared to pure opioid medicines.
      • Can help you fall asleep easier.
      Downsides and risks
      NorcoPercocet
      • Dizziness and drowsiness is common.
      • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Norco if you need.
      • The non-opioid part of Norco, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
      • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
      • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
      • Avoid alcohol.
      • Dizziness and drowsiness is common, but your body may adjust.
      • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
      • The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
      • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
      • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
      • Avoid alcohol.
      Tips from our pharmacists for people taking the medication
      NorcoPercocet
      • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
      • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
      • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
      • Use it for the shortest time and at the lowest dose possible, to lower your chance of becoming addicted.
      • Take it with food to lower the chance of an upset stomach.
      • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
      • Don't take more than instructed to prevent liver damage.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
      • Starts working in 30 minutes.
      • Works best if you take it as soon as you start feeling pain.
      • Pain relief lasts 4-6 hours.
      • Can make you dizzy or drowsy.
      • Avoid activities need you to be fully alert until you know how it affects you.
      • Use it for the shortest time possible, and at the lowest dose possible, to lower your chance of becoming addicted.
      • Take it with food to lower the chance of an upset stomach.
      • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
      • Don't take more than instructed to prevent liver damage.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      Learn more
      More about NorcoSide effectsReviews & ratingsAlternativesFDA package insert
      More about PercocetSide effectsReviews & ratingsAlternativesFDA package insert