Compare Norpramin vs. Pamelor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Norpramin
(Desipramine)

Pamelor
(Nortriptyline)

Coming soon.Improves your mood. Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.
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Reviews & ratings
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Have you used Norpramin (Desipramine)?
Worth itNot sureNot worth it

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Have you used Pamelor (Nortriptyline)?
Worth itNot sureNot worth it
Side effects
NorpraminPamelor

We haven’t found good data for Norpramin side effects.

FDA side effect reports for Norpramin »

We haven’t found good data for Pamelor side effects.

FDA side effect reports for Pamelor »
How it works
NorpraminPamelor
Coming soon.Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain.
Type of medication
NorpraminPamelor
Coming soon.
Antidepressant
Tricyclic antidepressant (TCA)
Prescription only
Available as
NorpraminPamelor
  • Pill
  • Pill
  • Liquid
Used for (click to learn more)
NorpraminPamelor
  • Depression
Risk factors for serious side effects
NorpraminPamelor
Coming soon.
  • Age 24 years or younger
  • Age 65 years or older
  • Stopping Pamelor (Nortriptyline) suddenly
  • Using other medications that affect serotonin
  • History of heart disease
  • Older age
  • Electrolyte imbalance
Detailed Pamelor (Nortriptyline) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Food
NorpraminPamelor
No food related info.
  • Take it with food and/or at bedtime to decrease the potential side effects.
Upsides and benefits
NorpraminPamelor
Coming soon
  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
Downsides and risks
NorpraminPamelor
Coming soon
  • Side effects are usually manageable, but can be annoying.
  • Increases the risk of falls, especially when used in the elderly.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
Tips from our pharmacists for people taking the medication
NorpraminPamelor
Coming soon
  • Needs to be taken every day for 1 to 2 weeks to start feeling better, and for 6 to 8 weeks to see the full effect of the medication.
  • It's important to keep taking Pamelor (Nortriptyline) even when you feel your symptoms are getting better.
  • Take it with food and/or at bedtime to decrease the potential side effects.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • If you decide to stop taking Pamelor (Nortriptyline), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
Learn more
More about NorpraminSide effectsReviews & ratingsFDA package insert
Have you used Norpramin (Desipramine)?
Worth itNot sureNot worth it
More about PamelorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pamelor (Nortriptyline)?
Worth itNot sureNot worth it