Compare Norvasc vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers blood pressure.

Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.

3.7/ 5 average rating with 443 reviewsforNorvasc
Lowers blood pressure and controls heart rate.

Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.

3.8/ 5 average rating with 164 reviewsforToprol XL
Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Extended release
Price
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Reviews
443 reviews so far
58%
saidit'sworth it
50%
saiditworked well
15%
saidit'sa big hassle

Have you used Norvasc (Amlodipine)?

Leave a review
164 reviews so far
60%
saidit'sworth it
54%
saiditworked well
13%
saidit'sa big hassle

Have you used Toprol XL (metoprolol succinate)?

Leave a review
Side effects
3possible side effects
  • Fatigue
    5%
  • Nausea
    3%
  • Abdominal pain
    2%
See more detailed side effects
2possible side effects
  • Dizziness/balance problems
    2%
  • Slower heartbeat
    2%
See more detailed side effects
Risks and risk factors
  • Low blood pressure
    • Age 65 years or older
  • Heart attack
    • History of heart problems
  • Special dosing requirements
    • Liver disease
  • Foot and leg swelling (edema)
    • History of blood vessel disease
    • History of heart failure
    • History of kidney disease
    • Obesity
See more detailed risks and warnings
  • Heart problems
    • Sudden discontinuation of medicine
    • Coronary artery disease
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
    • Hyperthyroidsim
  • Increased symptoms of heart failure
    • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Trouble breathing (bronchospastic disease)
    • History of asthma
    • History of COPD
See more detailed risks and warnings