Compare Novolog vs. Apidra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Novolog
(Insulin Aspart)

Apidra
(Insulin Glulisine)

Lowers blood sugar. Novolog is a fast-acting insulin that provides meal-time sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.Coming soon.
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Reviews & ratings
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4.77Novolog
Reviews for Novolog (Insulin Aspart)
58%
of people (All ages) say Novolog (Insulin Aspart) is worth it
46%
say it works well
19%
say it's a big hassle
177 reviews
Have you used Novolog (Insulin Aspart)?
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Have you used Apidra (Insulin Glulisine)?
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Side effects
NovologApidra
  • Decreased muscle reflexes 11%
  • Nail fungal infection 10%
  • Abnormal sense of touch 9%
  • Urinary tract infection 8%
  • Chest pain 5%
  • Headache 5%
  • Skin disorder 5%
  • Abdominal pain 5%
  • Sinus inflammation 5%
  • Injury accidental 11%
More Novolog side effects »

We haven’t found good data for Apidra side effects.

FDA side effect reports for Apidra »
How it works
NovologApidra
Novolog is a short-acting insulin medicine for diabetes. It acts like the insulin that your body normally makes to process sugars and fats, and it keeps your blood sugar stable after meals.Coming soon.
Type of medication
NovologApidra
Prescription only
Available as
NovologApidra
  • Injection
  • Injection
Used for
NovologApidra
  • Diabetes Mellitus Type 1 Diabetes Mellitus Type 2
Risk factors for serious side effects
NovologApidra
  • Insulin dose too high
  • Use of other blood sugar lowering medicines
  • Poor injection techniques
  • Unstable kidney functions
  • Unstable liver functions
  • Use of other medicine that lowers potassium
  • Current electrolyte imbalance
    Detailed Novolog (Insulin Aspart) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    NovologApidra
    • Novolog is a fast-acting insulin that provides sugar control after meals.
    • Short-acting insulin good for blood sugar control around meal times.
    No food related info.
    Kidneys and liver
    NovologApidra
    • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
    No kidneys and liver related info.
    Weight
    NovologApidra
    • Likely to cause moderate weight gain (around 4 to 6 pounds).
    • Can cause weight gain and low blood sugar.
    No weight related info.
    Upsides and benefits
    NovologApidra
    • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
    • Novolog is a fast-acting insulin that provides sugar control after meals.
    • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
    • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
    • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
    Coming soon
    Downsides and risks
    NovologApidra
    • You have to take insulin by injection.
    • You have to check your blood sugar multiple times every day, usually before each meal.
    • Likely to cause moderate weight gain (around 4 to 6 pounds).
    • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
    Coming soon
    Tips from our pharmacists for people taking the medication
    NovologApidra
    • Short-acting insulin good for blood sugar control around meal times.
    • Take 5 to 10 minutes before a meal. Effects last for 2-4 hours.
    • Can cause weight gain and low blood sugar.
    • Make sure you and your family know the symptoms of low blood sugar: sweating, shakiness, weakness, fast heartbeat, nervousness, headache, blurry vision, trouble thinking clearly, or passing out.
    • Always have a good source of sugar nearby for low blood sugar episodes.
    • Make sure you understand how to give yourself the injections.
    • When mixing with another insulin (such as insulin NPH), draw this insulin into the syringe first.
    • Don't shake the vial. Store unopened vials in the refrigerator. Opened vials are good at room temperature for 28 days.
    • Check your blood sugar levels every day.
    Coming soon
    Learn more
    More about NovologSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Novolog (Insulin Aspart)?
    Worth itNot sureNot worth it
    More about ApidraSide effectsReviews & ratingsFDA package insert
    Have you used Apidra (Insulin Glulisine)?
    Worth itNot sureNot worth it