Compare Oleptro vs. Ativan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Oleptro (Trazodone)

Prescription only

Ativan (lorazepam)

Prescription only
Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

4.9/ 7 average rating with 59 reviewsforOleptro
Helps you relax.

Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.

5.1/ 7 average rating with 642 reviewsforAtivan
Upsides
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
  • Effective at relieving short-term anxiety.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Downsides
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
  • Most people find that Ativan (lorazepam) gets less effective over time.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Liquid
  • Injection
Price
Lowest price near you
$4
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Lowest price near you
$9.17
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Reviews
59 
73%
think this treatment is worth it
49%
think this treatment works well
24%
think this treatment is a hassle

Have you used Oleptro (Trazodone)?

Leave a review
642 
71%
think this treatment is worth it
51%
think this treatment works well
15%
think this treatment is a hassle

Have you used Ativan (lorazepam)?

Leave a review
Side effects
9possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
See more detailed side effects
4possible side effects
  • Sleepiness
    16%
  • Dizziness
    7%
  • Weakness
    4%
  • Unsteadiness
    3%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Seizures

    History of seizures

    ...and 4 more risk factors

  • Low blood pressure

    Age 65 years or older

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Severe sedation with opioid use

    Taking with opioids

  • Tolerance and dependence

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Withdrawal

    Long-term use

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings