Compare Oleptro vs. Restoril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Oleptro
(Trazodone)

Restoril
(Temazepam)

Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.833333333333333Oleptro
Reviews for Oleptro (Trazodone)
72%
of people say Oleptro (Trazodone) is worth it
48%
say it works well
24%
say it's a big hassle
Reviews for Restoril (Temazepam)
56%
16% vs. Oleptro (Trazodone)
56%
+8% vs. Oleptro (Trazodone)
22%
+2% vs. Oleptro (Trazodone)
Side effects
OleptroRestoril
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Blurred vision 11%
  • Nausea 8%
  • Fatigue 7%
  • Skin condition/edema 6%
  • Headache 6%
More Oleptro side effects »

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »
How it works
OleptroRestoril
Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.
Type of medication
OleptroRestoril
Antidepressant
Serotonin antagonist and reuptake inhibitor
Prescription only
Anti-anxiety
Benzodiazepine
Prescription only
Available as
OleptroRestoril
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
OleptroRestoril
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Oleptro (Trazodone)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Restoril (Temazepam)
Risk factors for serious side effects
OleptroRestoril
  • Age 24 years or younger
  • History of seizures
  • Alcoholism
  • Eating disorder
  • Higher dose
  • Drug interactions
    • Age 65 years or older
    • Alcohol
    • Taking other medicines that make you less alert
    Detailed Oleptro (Trazodone) risks & warnings »
    • Taking more than the prescribed dose
    • Taking longer than 4 weeks
    • History of drug abuse
    • Long-term use
    • Women of childbearing age
    • Alcohol
    • Taking other medicines that make you less alert
      • Taking with alcohol
      • Taking with other drugs that acts in the brain
      • Age 65 or older
      Detailed Restoril (Temazepam) risks & warnings »
      Pregnancy category
      OleptroRestoril
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      XFDA pregnancy category (Unsafe)

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.
      • It is not safe to drink alcohol while taking this.
      • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      • Fewer sexual side effects than many other antidepressants.
      • Seek medical attention for unwanted, persistent erection.
      • Rarely, Oleptro (Trazodone) can cause a painful, persistent erection for 4 hours or more. Seek medical attention.
      No specific sex-related info.
      Sleep
      • Commonly used in lower doses to help treat sleep problems (insomnia).
      • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
      • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
      • Comes as a generic medication and is cheaper than many other sleep aides.
      • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
      • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
      • Use only as needed when you can't sleep.
      • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
      • Stopping Restoril (Temazepam) suddenly can cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and muscle pain or burning. Withdrawal symptoms can last 6 weeks or longer. Work with your doctor to gradually reduce your dose.
      • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      OleptroRestoril
      • Commonly used in lower doses to help treat sleep problems (insomnia).
      • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
      • Fewer sexual side effects than many other antidepressants.
      • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
      • Comes as a generic medication and is cheaper than many other sleep aides.
      • Six out of ten people who use an antidepressant for the first time find that it works for them.
      • Helps you fall asleep and stay asleep.
      • Can be helpful to reduce anxiety.
      • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
      Downsides and risks
      OleptroRestoril
      • Not as effective as other medications for depression.
      • More sedating than other antidepressants.
      • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
      • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
      • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
      • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
      • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
      • It's not recommended for people age 65 years or older.
      • Can't be used by pregnant women since it'll cause harm to the baby.
      • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
      Tips from our pharmacists for people taking the medication
      OleptroRestoril
      • Makes you sleepy. Take at bedtime.
      • Can cause temporary dry mouth and upset stomach.
      • Seek medical attention for unwanted, persistent erection.
      • Tell your doctor if you notice sudden mood changes or unusual thoughts.
      • Use only as needed when you can't sleep.
      • Starts working within 45 minutes.
      • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
      • Take it only if you can get a full night's rest.
      • It is not safe to drink alcohol while taking this.
      • Tell your doctor if you notice any changes to your memory or mood.
      Learn more
      More about OleptroSide effectsReviews & ratingsAlternativesFDA package insert
      More about RestorilSide effectsReviews & ratingsAlternativesFDA package insert