Compare Omega 3 Acid vs. Simvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lovaza
(Omega-3 Acid)

Zocor
(Simvastatin)

Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.Lowers cholesterol. Zocor (Simvastatin) is a good medication to improve your cholesterol. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.956521739130435Omega 3 Acid
Reviews for Lovaza (Omega-3 Acid)
59%
of people say Lovaza (Omega-3 Acid) is worth it
50%
say it works well
28%
say it's a big hassle
Reviews for Zocor (Simvastatin)
61%
+2% vs. Lovaza (Omega-3 Acid)
48%
2% vs. Lovaza (Omega-3 Acid)
14%
+14% vs. Lovaza (Omega-3 Acid)
Side effects
Omega 3 AcidSimvastatin
  • Eructation 3%
  • Indigestion 1%
More Omega 3 Acid side effects »
  • Upset stomach 3%
  • Scaly, itchy rash 2%
  • Bronchitis 1%
  • Vertigo 1%
  • Muscle pain 1%
  • Edema/swelling 1%
  • Abnormal heart rhythm 1%
More Simvastatin side effects »
How it works
Omega 3 AcidSimvastatin
Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.Zocor (Simvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
Omega 3 AcidSimvastatin
Cholesterol-lowering
Omega-3 fatty acid
Prescription only
Cholesterol-lowering
Statin
Prescription only
Available as
Omega 3 AcidSimvastatin
  • Pill
  • Pill
  • Dissolving tablet
Used for (click to learn more)
Omega 3 AcidSimvastatin
Risk factors for serious side effects
Omega 3 AcidSimvastatin
  • Allergy to fish or shellfish
  • Atrial fibrillation
Detailed Lovaza (Omega-3 Acid) risks & warnings »
  • Kidney disease
  • High dose of Zocor (Simvastatin)
  • Combining Zocor (Simvastatin) with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
  • History of chronic liver disease
  • Pregnancy
  • Breast feeding
  • Certain drugs can increase the dose of Zocor (Simvastatin) in the body
    Detailed Zocor (Simvastatin) risks & warnings »
    Pregnancy category
    Omega 3 AcidSimvastatin
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    XFDA pregnancy category (Unsafe)

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
    • There are reports of liver damage in people who take Zocor (Simvastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
    Food
    • You have to take it with food.
    • Take it with food.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
    • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
    • There are rare cases of muscle damage leading to kidney failure in people taking Zocor (Simvastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
    • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Omega 3 AcidSimvastatin
    • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
    • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
    • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
    • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
    Downsides and risks
    Omega 3 AcidSimvastatin
    • You can't take it if you're allergic to fish or shellfish.
    • You have to take it with food.
    • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
    • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
    • Not safe to use if you're pregnant.
    Tips from our pharmacists for people taking the medication
    Omega 3 AcidSimvastatin
    • Lowers triglycerides.
    • Take it with food.
    • Swallow capsules whole.
    • Can cause burping and changes in taste.
    • Don't use if you have an allergy to fish or shellfish.
    • You should use this medicine in combination with a healthy diet.
    • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
    • Most people reach their target cholesterol levels in 4 to 6 weeks.
    • Avoid grapefruit and grapefruit juice while taking this medicine.
    • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
    • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
    • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
    Learn more
    More about Omega 3 AcidSide effectsReviews & ratingsAlternativesFDA package insert
    More about SimvastatinSide effectsReviews & ratingsAlternativesFDA package insert