Compare Omega 3 Acid vs. Vytorin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

(omega-3 acid)

(ezetimibe / simvastatin)

Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.Lowers cholesterol. Vytorin is expensive and is no more effective than simvastatin by itself.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Omega 3 Acid
Best available price for 120 (1g) capsules of omega-3-acid-ethyl-esters
Coupons for Vytorin
Best available price for 30 (10mg/40mg) tablets of vytorin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.96Omega 3 Acid
Reviews for Omega 3 Acid
of people (All ages) say Omega 3 Acid is worth it
say it works well
say it's a big hassle
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it
Reviews for Vytorin
+6% better vs. Omega 3 Acid
+14% better vs. Omega 3 Acid
-9% worse vs. Omega 3 Acid
Have you used Vytorin (ezetimibe / simvastatin)?
Worth itNot sureNot worth it
Side effects
Omega 3 AcidVytorin
  • Eructation 3%
  • Change in taste 4%
  • Indigestion 1%
More Omega 3 Acid side effects »
  • Headache 1%
  • Any side effect 3%
  • Muscle pain 4%
  • Ear, nose, or throat infection 4%
  • Increased alt 4%
  • Diarrhea 3%
  • Flu 1%
  • Pain in extremity 1%
  • Unexplained muscle pain or weakness 1%
More Vytorin side effects »
How it works
Omega 3 AcidVytorin
Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.Vytorin is a combination cholesterol-lowering medicine. Simvastatin prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). Ezetimibe prevents cholesterol absorption in your intestines.
Type of medication
Omega 3 AcidVytorin
Prescription onlyPrescription only
Available as
Omega 3 AcidVytorin
  • Pill
  • Pill
Used for
Omega 3 AcidVytorin
Risk factors for serious side effects
Omega 3 AcidVytorin
  • Allergy to fish or shellfish
  • Atrial fibrillation
Detailed Lovaza (omega-3 acid) risks & warnings »
  • Asian patients taking high-dose niacin
  • Past history of liver disease
  • heavy alcohol use
  • Diabetes
  • Pregnancy
Detailed Vytorin (ezetimibe / simvastatin) risks & warnings »

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Omega 3 AcidVytorin
  • Take it with food.
  • You have to take it with food.
No food related info.
Kidneys and liver
Omega 3 AcidVytorin
No kidneys and liver related info.
  • People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.
Upsides and benefits
Omega 3 AcidVytorin
  • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
  • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
Downsides and risks
Omega 3 AcidVytorin
  • You can't take it if you're allergic to fish or shellfish.
  • You have to take it with food.
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
Tips from our pharmacists for people taking the medication
Omega 3 AcidVytorin
  • Lowers triglycerides.
  • Take it with food.
  • Swallow capsules whole.
  • Can cause burping and changes in taste.
  • Don't use if you have an allergy to fish or shellfish.
  • You should use this medicine in combination with a healthy diet.
  • Take it in the evening.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Can cause headaches or diarrhea.
  • Call your doctor if you develop muscle pain.
  • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
Learn more
More about Omega 3 AcidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it
More about VytorinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Vytorin (ezetimibe / simvastatin)?
Worth itNot sureNot worth it