Compare Omega 3 Acid vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lovaza
(Omega-3 Acid)

Zetia
(Ezetimibe)

Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.956521739130435Omega 3 Acid
Reviews for Lovaza (Omega-3 Acid)
59%
of people say Lovaza (Omega-3 Acid) is worth it
50%
say it works well
28%
say it's a big hassle
Reviews for Zetia (Ezetimibe)
42%
17% vs. Lovaza (Omega-3 Acid)
34%
16% vs. Lovaza (Omega-3 Acid)
20%
+8% vs. Lovaza (Omega-3 Acid)
Side effects
Omega 3 AcidZetia
  • Eructation 3%
  • Indigestion 1%
More Omega 3 Acid side effects »
  • Ear, nose, or throat infection 1%
  • Sinus inflammation 1%
  • Arthtralgia 1%
More Zetia side effects »
How it works
Omega 3 AcidZetia
Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.
Type of medication
Omega 3 AcidZetia
Cholesterol-lowering
Omega-3 fatty acid
Prescription only
Cholesterol-lowering
Cholesterol inhibitor
Prescription only
Available as
Omega 3 AcidZetia
  • Pill
  • Pill
Used for (click to learn more)
Omega 3 AcidZetia
Risk factors for serious side effects
Omega 3 AcidZetia
  • Allergy to fish or shellfish
  • Atrial fibrillation
Detailed Lovaza (Omega-3 Acid) risks & warnings »
    • Taking Zetia (Ezetimibe) with statins
    • Past history of liver disease
    • Taking Zetia (Ezetimibe) with statins
    Detailed Zetia (Ezetimibe) risks & warnings »
    Pregnancy category
    Omega 3 AcidZetia
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • You have to take it with food.
    • Take it with food.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • People on Zetia (Ezetimibe) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Omega 3 AcidZetia
    • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
    • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
    • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
    • Can be used with other medicines to improve cholesterol.
    • Available in a combination pill with simvastatin.
    Downsides and risks
    Omega 3 AcidZetia
    • You can't take it if you're allergic to fish or shellfish.
    • You have to take it with food.
    • Doesn't lower triglycerides (fats).
    • Hasn't been shown to lower the risk of heart attacks or heart disease.
    • By itself, Zetia is not as effective as statins for improving cholesterol.
    • There's no generic available, so it can be expensive.
    Tips from our pharmacists for people taking the medication
    Omega 3 AcidZetia
    • Lowers triglycerides.
    • Take it with food.
    • Swallow capsules whole.
    • Can cause burping and changes in taste.
    • Don't use if you have an allergy to fish or shellfish.
    • You should use this medicine in combination with a healthy diet.
    • Lowers bad cholesterol, and raises good cholesterol.
    • Tell your doctor if you develop bone or muscle pain.
    • Can be used with other medications to lower cholesterol.
    • May cause diarrhea or raise your chance of getting colds.
    Learn more
    More about Omega 3 AcidSide effectsReviews & ratingsAlternativesFDA package insert
    More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert