Improves your mood. Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain. Improves mood and relieves certain kinds of pain. Cymbalta (Duloxetine) is good for treating depression and anxiety, and may help with chronic pain. More likely than other antidepressants to cause problems if you drink or have high blood pressure. Find lowest prices Save on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance. Reviews & ratings Everyone Men Women Filter group. All currently selected Everyone Men Women All ages 18-34 35-54 55+ Filter group. All currently selected All ages 18-34 35-54 55+
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Reviews for Cymbalta (Duloxetine)
vs. Pamelor (Nortriptyline)
28% vs. Pamelor (Nortriptyline)
9% vs. Pamelor (Nortriptyline)
Side effects Pamelor Cymbalta
We haven’t found good data for Pamelor side effects.
FDA side effect reports for Pamelor »
Dry mouth 8%
Decreased appetite 7%
Sleep difficulty 5%
More Cymbalta side effects » How it works Pamelor Cymbalta Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain. Cymbalta (Duloxetine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulates mood. Type of medication Pamelor Cymbalta Antidepressant
› Tricyclic antidepressant (TCA)
Prescription only Antidepressant
› Serotonin-norepinephrine reuptake inhibitor (SNRI)
Prescription only Available as Pamelor Cymbalta Used for (click to learn more) Pamelor Cymbalta Risk factors for serious side effects Pamelor Cymbalta › Age 24 years or younger › Stopping Pamelor (Nortriptyline) suddenly › Using other medications that affect serotonin › History of heart disease › Older age › Electrolyte imbalance Detailed Pamelor (Nortriptyline) risks & warnings » › Age 24 years or younger › Using other medications that affect serotonin › Stopping Cymbalta (Duloxetine) suddenly › History of high blood pressure › Taking other blood-thinning drugs › History of bipolar disorder › At risk for bipolar disorder Detailed Cymbalta (Duloxetine) risks & warnings »
The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.
Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.
Food Pamelor Cymbalta › Take it with food and/or at bedtime to decrease the potential side effects. › Take with food to avoid upset stomach.
Kidneys and liver Pamelor Cymbalta No kidneys and liver related info. › Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
Pain Pamelor Cymbalta No pain related info. › Full effects in 8 to 12 weeks for mood, 2 weeks for pain. Upsides and benefits Pamelor Cymbalta › Helpful with treating certain types of pain, like migraines or nerve-related pain. › Generally well tolerated and has fewer side effects than other medicines in the same class of drugs. › Effective at relieving depression and anxiety symptoms. › Lowers relapse rates for depression. › Can relieve some types of chronic pain. Might be particularly good at pain relief for people who are also depressed. › Six out of ten people who use an antidepressant for the first time find that it works for them. Downsides and risks Pamelor Cymbalta › Side effects are usually manageable, but can be annoying. › Increases the risk of falls, especially when used in the elderly. › There's an increased chance of it causing heart problems, especially in people with a history of heart problems. › Not a good option if you're a heavy drinker, or if you have liver or kidney problems. › Not the best option for people with high blood pressure. › Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger. › The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you. Tips from our pharmacists for people taking the medication Pamelor Cymbalta › Needs to be taken every day for 1 to 2 weeks to start feeling better, and for 6 to 8 weeks to see the full effect of the medication. › It's important to keep taking Pamelor (Nortriptyline) even when you feel your symptoms are getting better. › Take it with food and/or at bedtime to decrease the potential side effects. › If you decide to stop taking Pamelor (Nortriptyline), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms. › Tell your doctor if you notice sudden mood changes or unusual thoughts. › Take with food to avoid upset stomach. › Full effects in 8 to 12 weeks for mood, 2 weeks for pain. › Stop taking slowly to avoid withdrawal symptoms. › Tell your doctor if you notice sudden mood changes or unusual thoughts. Learn more More about Pamelor Side effects Reviews & ratings Alternatives FDA package insert More about Cymbalta Side effects Reviews & ratings Alternatives FDA package insert