Compare Pamelor vs. Neurontin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pamelor (Nortriptyline)

Prescription only

Neurontin (gabapentin)

Prescription only
Improves your mood.

Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.

4.0/ 5 average rating with 19 reviewsforPamelor
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

3.4/ 5 average rating with 620 reviewsforNeurontin
Upsides
  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
Downsides
  • Side effects are usually manageable, but can be annoying.
  • Increases the risk of falls, especially when used in the elderly.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Oral solution
  • Extended release
Price
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Reviews
19 reviews so far
79%
saidit'sworth it
79%
saiditworked well
21%
saidit'sa big hassle

Have you used Pamelor (Nortriptyline)?

Leave a review
620 reviews so far
57%
saidit'sworth it
40%
saiditworked well
19%
saidit'sa big hassle

Have you used Neurontin (gabapentin)?

Leave a review
Side effects
The Pamelor (Nortriptyline) FDA package insert doesn’t have numbers about how common side effects are.
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Low blood pressure
    • Age 65 years or older
  • Withdrawal
    • Stopping Pamelor (Nortriptyline) suddenly
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Heart problems
    • History of heart disease
    • Older age
    • Electrolyte imbalance
See more detailed risks and warnings
  • Suicidal thoughts or behavior
  • Neurologic and psychiatric side effects (children)
    • Children ages 3 to 12
  • Serious allergic reaction and multiple organ problems
  • Driving impairment
    • Taking Neurontin (gabapentin) with alcohol
    • Taking other medicines that cause dizziness and/or drowsiness
  • Withdrawal seizures
    • Stopping Neurontin (gabapentin) suddenly
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.