Compare Paxil vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Paxil (paroxetine)

Prescription only

Oleptro (Trazodone)

Prescription only
Improves mood and anxiety.

Paxil (paroxetine) is effective for treating depression and anxiety, but causes more unwanted side-effects than other medicines that work like it.

4.5/ 7 average rating with 694 reviewsforPaxil
Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

4.9/ 7 average rating with 59 reviewsforOleptro
Upsides
  • Available in a cheaper, generic form.
  • Is convenient and can take once a day.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
  • More likely to decrease your sexual appetite and delay or prevent ejaculation than other antidepressants.
  • Like most antidepressants, Paxil (paroxetine) has a high risk of suicidal thoughts and behavior when used in children and adolescents.
  • May not be appropriate for you if you are elderly or suffer from dementia.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
Dosage forms
  • Pill
  • Extended release pill
  • Liquid
  • Pill
  • Extended release
Price
Lowest price near you
$4
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Lowest price near you
$4
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Reviews
694 
52%
think this treatment is worth it
39%
think this treatment works well
24%
think this treatment is a hassle

Have you used Paxil (paroxetine)?

Leave a review
59 
73%
think this treatment is worth it
49%
think this treatment works well
24%
think this treatment is a hassle

Have you used Oleptro (Trazodone)?

Leave a review
Side effects
10possible side effects
  • Abnormal ejaculation
    28%
  • Nausea
    25%
  • Weakness
    22%
  • Drowsiness
    22%
  • Difficulty sleeping
    21%
  • Decreased sexual appetite
    12%
  • Dizziness
    11%
  • Sweating
    9%
  • Dry mouth
    9%
  • Diarrhea
    9%
See more detailed side effects
9possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • High levels of serotonin (Serotonin Syndrome)

    Using other medications that affect serotonin levels

  • Withdrawal

    Stopping Paxil (paroxetine) suddenly

  • Increased bleeding risk

    Taking other blood-thinning drugs

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Seizures

    History of seizures

    ...and 4 more risk factors

  • Low blood pressure

    Age 65 years or older

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings