Compare Paxil vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Paxil (paroxetine)

Prescription only

Remeron (mirtazapine)

Prescription only
Improves mood and anxiety.

Paxil (paroxetine) is effective for treating depression and anxiety, but causes more unwanted side-effects than other medicines that work like it.

3.4/ 5 average rating with 694 reviewsforPaxil
Improves mood.

Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.

3.3/ 5 average rating with 152 reviewsforRemeron
Upsides
  • Available in a cheaper, generic form.
  • Is convenient and can take once a day.
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
Downsides
  • More likely to decrease your sexual appetite and delay or prevent ejaculation than other antidepressants.
  • Like most antidepressants, Paxil (paroxetine) has a high risk of suicidal thoughts and behavior when used in children and adolescents.
  • May not be appropriate for you if you are elderly or suffer from dementia.
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Used for
Dosage forms
  • Pill
  • Extended release pill
  • Liquid
  • Pill
  • Dissolving tablet
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
694 reviews so far
52%
saidit'sworth it
39%
saiditworked well
24%
saidit'sa big hassle

Have you used Paxil (paroxetine)?

Leave a review
152 reviews so far
45%
saidit'sworth it
39%
saiditworked well
26%
saidit'sa big hassle

Have you used Remeron (mirtazapine)?

Leave a review
Side effects
29possible side effects
  • Abnormal ejaculation
    28%
  • Nausea
    25%
  • Weakness
    22%
  • Drowsiness
    22%
  • Difficulty sleeping
    21%
  • Decreased sexual appetite
    12%
  • Dizziness
    11%
  • Sweating
    9%
  • Dry mouth
    9%
  • Diarrhea
    9%
  • Tremor
    9%
  • Female genital disorder
    9%
  • Decreased appetite
    8%
  • Nervousness
    8%
  • Constipation
    5%
  • Anxiety
    5%
  • Yawning
    5%
  • Painful period
    5%
  • Impotence
    5%
  • Indigestion
    4%
  • Gas
    4%
  • Muscle pain
    4%
  • Impaired concentration
    4%
  • Throat inflammation
    4%
  • Abnormal vision
    4%
  • Trauma
    3%
  • Agitation
    3%
  • Vomiting
    2%
  • Muscle twitching
    2%
See more detailed side effects
The Remeron (mirtazapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • High levels of serotonin (Serotonin Syndrome)
    • Using other medications that affect serotonin levels
  • Withdrawal
    • Stopping Paxil (paroxetine) suddenly
  • Increased bleeding risk
    • Taking other blood-thinning drugs
  • Sexual dysfunction
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Heart problems
    • History of heart problems
    • History of liver problems
    • Higher dose
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Weight gain
  • Blood disorders
See more detailed risks and warnings
Now you can ask a pharmacist!

What is your question about?

Your question

Your email

We need your email to send you an answer.

Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.