Compare Pepcid vs. Tums

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pepcid (Famotidine)

Prescription or OTC

Tums (Calcium carbonate)

Over-the-counter
Relieves heartburn.

Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.

5.1/ 7 average rating with 853 reviewsforPepcid
Relieves heartburn.

Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.

5.2/ 7 average rating with 1373 reviewsforTums
Upsides
  • Most people can take Famotidine without any noticeable day-to-day side effects.
  • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Few drug interactions.
  • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
  • Tums (Calcium carbonate) starts working in seconds.
  • Has minimal side effects.
  • Available in chewable form.
  • Is inexpensive and readily available over-the-counter.
  • Coupons are available – speak to your doctor or pharmacist.
Downsides
  • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
  • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
  • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
  • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
  • May increase calcium levels too much in people with kidney or thyroid conditions.
  • May have a chalky taste.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
Price
Lowest price near you
$4
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Reviews
853 
75%
think this treatment is worth it
41%
think this treatment works well
8%
think this treatment is a hassle

Have you used Pepcid (Famotidine)?

Leave a review
1373 
82%
think this treatment is worth it
43%
think this treatment works well
5%
think this treatment is a hassle

Have you used Tums (Calcium carbonate)?

Leave a review
Side effects
2possible side effects
  • Headache
    5%
  • Diarrhea
    2%
See more detailed side effects
The Tums (Calcium carbonate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased side effects

    Current kidney disease

See more detailed risks and warnings
No information currently available