Compare Pepcid vs. Tums

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pepcid
(famotidine)

Tums
(calcium carbonate)

Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.09Pepcid
Reviews for Pepcid
75%
of people (All ages) say Pepcid is worth it
41%
say it works well
8%
say it's a big hassle
853 reviews
Have you used Pepcid (famotidine)?
Worth itNot sureNot worth it
Reviews for Tums
82%
-7% worse vs. Pepcid
43%
-2% worse vs. Pepcid
5%
-3% worse vs. Pepcid
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Side effects
PepcidTums
  • Headache 5%
  • Diarrhea 2%
More Pepcid side effects »

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »
How it works
PepcidTums
Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.
Type of medication
PepcidTums
Prescription or OTCOver-the-counter
Available as
PepcidTums
  • Pill
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
Used for
PepcidTums
Risk factors for serious side effects
PepcidTums
  • Current kidney disease
Detailed Pepcid (famotidine) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Interactions
    PepcidTums
    • Few drug interactions.
    No interactions related info.
    Kidneys and liver
    PepcidTums
    • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    Upsides and benefits
    PepcidTums
    • Most people can take Famotidine without any noticeable day-to-day side effects.
    • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Few drug interactions.
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    Downsides and risks
    PepcidTums
    • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
    • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    Tips from our pharmacists for people taking the medication
    PepcidTums
    • Short-term treatment of ulcers and acid reflux.
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    Learn more
    More about PepcidSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Pepcid (famotidine)?
    Worth itNot sureNot worth it
    More about TumsSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tums (calcium carbonate)?
    Worth itNot sureNot worth it