Compare perphenazine vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trilafon (perphenazine)

Prescription only

Abilify (aripiprazole)

Prescription only
Treats schizophrenia.

Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.

Helps control your thoughts and mood.

Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.

4.3/ 7 average rating with 252 reviewsforAbilify
Upsides
  • Trilafon (perphenazine) can be much cheaper than other medicines.
  • Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
Downsides
  • You're more likely to gain weight.
  • You can be more sensitive to temperature changes.
  • You're more likely to catch colds and flu.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Price
No pricing information available
Lowest price near you
$35.45
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Reviews
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252 
44%
think this treatment is worth it
40%
think this treatment works well
34%
think this treatment is a hassle

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Side effects
The Trilafon (perphenazine) FDA package insert doesn’t have numbers about how common side effects are.
The Abilify (aripiprazole) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Higher risk of death

    People age 65 or older with dementia and psychosis

  • Sleepiness

    Drinking alcohol or taking narcotics

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Suicidal thoughts or behavior

    Age 24 years or younger

    ...and 1 more risk factors

  • Increased blood sugar and cholesterol, and weight gain

    People with diabetes

    ...and 1 more risk factors

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings