Compare perphenazine vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trilafon (perphenazine)

Prescription only
Treats schizophrenia.

Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.

Treats schizophrenia or psychosis.

Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.

Upsides
  • Trilafon (perphenazine) can be much cheaper than other medicines.
  • Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
Downsides
  • You're more likely to gain weight.
  • You can be more sensitive to temperature changes.
  • You're more likely to catch colds and flu.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Used for
Dosage forms
  • Pill
  • Injection
No pricing information available
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
The Trilafon (perphenazine) FDA package insert doesn’t have numbers about how common side effects are.
The Prolixin Decanoate (fluphenazine decanoate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Higher risk of death

    People age 65 or older with dementia and psychosis

  • Sleepiness

    Drinking alcohol or taking narcotics

See more detailed risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

See more detailed risks and warnings