Compare perphenazine vs. Zyprexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trilafon (perphenazine)

Prescription only

Zyprexa (olanzapine)

Prescription only
Treats schizophrenia.

Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.

Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

5.1/ 7 average rating with 68 reviewsforZyprexa
Upsides
  • Trilafon (perphenazine) can be much cheaper than other medicines.
  • Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
Downsides
  • You're more likely to gain weight.
  • You can be more sensitive to temperature changes.
  • You're more likely to catch colds and flu.
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Injection
Price
No pricing information available
Lowest price near you
$12.05
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Reviews
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68 
41%
think this treatment is worth it
51%
think this treatment works well
51%
think this treatment is a hassle

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Side effects
The Trilafon (perphenazine) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
Risks and warnings
  • Higher risk of death

    People age 65 or older with dementia and psychosis

  • Sleepiness

    Drinking alcohol or taking narcotics

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Higher blood sugar, high cholesterol, and weight gain

    People with diabetes

    ...and 1 more risk factors

See more detailed risks and warnings