Compare phenelzine vs. Emsam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Nardil
(phenelzine)

Eldepryl
(selegiline)

Stabilizes your mood. Nardil (phenelzine) is not a first choice for treating depression, but it can be good if other medicines haven't worked. It can interact with a lot of medicines, and you have to avoid certain foods and alcohol.Coming soon.
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Coupons for phenelzine
Best available price for 120 (15mg) tablets of phenelzine
Coupons for Emsam
Best available price for 60 (5mg) tablets of selegiline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Nardil (phenelzine)
Not enough review data. Review it!
of people (All ages) say Nardil (phenelzine) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Nardil (phenelzine)?
Worth itNot sureNot worth it
Reviews for Eldepryl (selegiline)
Not enough review data. Review it!
Same vs. Nardil (phenelzine)
Not enough review data. Review it!
Same vs. Nardil (phenelzine)
Not enough review data. Review it!
-80% worse vs. Nardil (phenelzine)
Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it
Side effects
phenelzineEmsam

The phenelzine FDA package insert doesn’t have numbers about how common side effects are.

More about phenelzine side effects »

We haven’t found good data for Emsam side effects.

FDA side effect reports for Emsam »
How it works
phenelzineEmsam
Nardil (phenelzine) is a monoamine oxidase inhibitor. It raises the amount of certain chemicals in your body that are thought to regulate mood, such as norepinephrine, dopamine, and serotonin.Coming soon.
Type of medication
phenelzineEmsam
Prescription only
Available as
phenelzineEmsam
  • Pill
  • Pill
  • Patch
Used for
phenelzineEmsam
  • Major Depressive Disorder
Risk factors for serious side effects
phenelzineEmsam
  • People under age 24
  • Eating smoked meats, cheese, soy sauce, or fermented foods
  • Drinking beer or wine
  • Consuming an excessive amount of chocolate or caffeine
  • Taking cough and cold medicines like dextromethorphan (Robitussin DM) or pseudoephedrine (Sudafed)
Detailed Nardil (phenelzine) risks & warnings »
    Coming soon.
    Pregnancy

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    phenelzineEmsam
    • Avoid alcohol and limit the amount of caffeine you take if you take Nardil (phenelzine).
    • Eating certain foods or drinking beer or wine while taking Nardil (phenelzine) can cause your blood pressure to become dangerously high. Talk to your doctor or go to the emergency room right away if you get a very bad headache, changes in your heart rate, neck stiffness or soreness, or nausea and vomiting.
    No alcohol related info.
    Food
    phenelzineEmsam
    • Eating certain foods or drinking beer or wine while taking Nardil (phenelzine) can cause your blood pressure to become dangerously high. Talk to your doctor or go to the emergency room right away if you get a very bad headache, changes in your heart rate, neck stiffness or soreness, or nausea and vomiting.
    No food related info.
    Weight
    phenelzineEmsam
    • Nardil (phenelzine) can cause weight gain.
    No weight related info.
    Upsides and benefits
    phenelzineEmsam
    • Available in generic.
    Coming soon
    Downsides and risks
    phenelzineEmsam
    • Not a recommended first or second choice for depression because of the side effects and diet restrictions.
    • You'll need to restrict your diet because your blood pressure can get very high.
    • If you're switched to another antidepressant from Nardil (phenelzine), you'll have to wait at least 14 days before you can start, otherwise it can be very dangerous.
    Coming soon
    Tips from our pharmacists for people taking the medication
    phenelzineEmsam
    • If you're switching from Nardil (phenelzine) to another antidepressant, you have to wait at least 2 weeks after stopping Nardil (phenelzine) to safely start the new one.
    • Avoid smoked meats, cheese, soy sauce, and other fermented foods because Nardil (phenelzine) can raise your blood pressure.
    • Nardil (phenelzine) can cause weight gain.
    • You might not notice any changes in your mood until you've taken Nardil (phenelzine) for at least 4 weeks.
    • Don't stop taking Nardil (phenelzine) suddenly without talking to your doctor first.
    • Avoid alcohol and limit the amount of caffeine you take if you take Nardil (phenelzine).
    Coming soon
    Learn more
    More about phenelzineSide effectsAlternativesFDA package insert
    Have you used Nardil (phenelzine)?
    Worth itNot sureNot worth it
    More about EmsamSide effectsReviews & ratingsFDA package insert
    Have you used Eldepryl (selegiline)?
    Worth itNot sureNot worth it