Compare Phenylephrine vs. Dimetapp Cold and Allergy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sudafed Pe
(Phenylephrine)

Dimetapp Cold And Allergy
(Phenylephrine / Brompheniramine)

Clears your sinuses. Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects.Relieves congestion and allergy symptoms for kids. Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is good for multiple nasal symptoms, but it can make you really drowsy.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
No pricing data for this drug at this filter setting. Try searching onGoodRx
Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.171779141104294Phenylephrine
Reviews for Sudafed Pe (Phenylephrine)
44%
of people say Sudafed Pe (Phenylephrine) is worth it
23%
say it works well
10%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
PhenylephrineDimetapp Cold and Allergy

We haven’t found good data for Phenylephrine side effects.

FDA side effect reports for Phenylephrine »

We haven’t found good data for Dimetapp Cold and Allergy side effects.

FDA side effect reports for Dimetapp Cold and Allergy »
How it works
PhenylephrineDimetapp Cold and Allergy
Sudafed Pe (Phenylephrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Phenylephrine (a decongestant) clears your sinuses.
Type of medication
PhenylephrineDimetapp Cold and Allergy
DecongestantPrescription or OTC
DecongestantAntihistamine
1st generation
Over-the-counter
Available as
PhenylephrineDimetapp Cold and Allergy
  • Pill
  • Nasal spray
  • Eye drops
  • Suppository
  • Chewable tablet
  • Liquid
Used for (click to learn more)
PhenylephrineDimetapp Cold and Allergy
Risk factors for serious side effects
PhenylephrineDimetapp Cold and Allergy
  • History of high blood pressure
  • Taking MAO inhibitors
  • History of heart problems
  • Age 65 years or older
  • Women of childbearing age
Detailed Sudafed Pe (Phenylephrine) risks & warnings »
  • Taking with alcohol
  • Taking with other medicines that make you less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
  • Age 65 years or older
  • Glaucoma
  • Benign prostatic hypertrophy (BPH)
Detailed Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) risks & warnings »
Pregnancy category
PhenylephrineDimetapp Cold and Allergy
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • Shouldn't use it before you want to sleep.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
PhenylephrineDimetapp Cold and Allergy
  • Works to clear nasal congestion and helps you breathe better.
  • Helpful in relieving congestion-related headaches.
  • Has fewer side effects than other decongestants like pseudoephedrine.
  • It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Doesn't give you rebound congestion (worse symptoms when you stop taking it) like nasal spray decongestants do.
  • Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine with a decongestant and an antihistamine that's helpful in treating nasal symptoms related to cold and allergy.
  • Brompheniramine (the antihistamine) is useful for itchy eyes, runny nose, or constant sneezing.
  • Phenylephrine (the decongestant) is good for relieving congestion.
Downsides and risks
PhenylephrineDimetapp Cold and Allergy
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed).
  • You shouldn't use it if you have high blood pressure.
  • Can make your heart race or make you feel anxious and restless.
  • Shouldn't use it before you want to sleep.
  • Not as effective after using it for 4 days in a row.
  • If you don't really need both of the medications in this combination, you'd be taking extra medicine and might have extra side effects for no reason.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • Phenylephrine (the decongestant) doesn't last as long as other oral decongestants like pseudoephedrine, but can cause jitteriness.
  • The two medications in this medicine can somewhat work against each other, with one making you sleepy and the other making you jittery.
Tips from our pharmacists for people taking the medication
PhenylephrineDimetapp Cold and Allergy
  • Starts working in 30 minutes.
  • Phenylephrine can make you restless, so don't take it too close to bedtime.
  • It's in other cold and flu combination medicines. Read labels closely so you don't accidentally double up and take too much of it in a day.
  • Follow age-specific dosing instructions on how much to take.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Only use the provided dosage cup to measure the medicine. Don't use a spoon.
  • Follow the age-specific dosing instructions on how much to take. Don't take more than what's recommended on the package.
  • Talk to a doctor if the symptoms don't get better in 1 week.
Learn more
More about PhenylephrineSide effectsReviews & ratingsAlternativesFDA package insert
More about Dimetapp Cold and AllergySide effectsReviews & ratingsAlternativesFDA package insert