Compare pilocarpine vs. Iopidine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Salagen
(Pilocarpine)

Iopidine
(Apraclonidine)

lowers eye pressure A very effective first line treatment for increased eye pressure. Lowering eye pressure back to normal may prevent the onset of glaucoma.Lowers eye pressure .Iopidine is used before and after laser surgery to prevent increased eye pressure due to the surgery.
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Reviews & ratings
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Side effects
pilocarpineIopidine

We haven’t found good data for pilocarpine side effects.

FDA side effect reports for pilocarpine »

We haven’t found good data for Iopidine side effects.

FDA side effect reports for Iopidine »
How it works
pilocarpineIopidine
pilocarpine increases the flow of fluids out of the inner eye.Iopidine reduces the fluid production within the eye, and increases the flow of fluids out of the eye.
Type of medication
pilocarpineIopidine
Coming soon.
Coming soon.
Available as
pilocarpineIopidine
  • Eye drops
  • Eye drops
Used for (click to learn more)
pilocarpineIopidine
  • Head and neck cancer - Radiation-induced xerostomia Raised intraocular pressure Sjögren's syndrome - Xerostomia
  • Laser surgery - Ocular hypertension
Risk factors for serious side effects
pilocarpineIopidine
Coming soon.Coming soon.
Pregnancy category
pilocarpineIopidine
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
pilocarpineIopidine
  • pilocarpine is often used with other drugs to control eye pressure.
  • Iopidine helps to get better results from laser surgery.
Downsides and risks
pilocarpineIopidine
  • pilocarpine causes the pupil of the eye to become smaller, and may cause dim vision, especially at night, therefore driving at night may be impaired.
  • May cause changes in your heart rate, slower or pounding.
  • may cause shortness of breath.
Tips from our pharmacists for people taking the medication
pilocarpineIopidine
  • Wash hands before putting drops in eyes.
  • Do not touch the dropper tip to your eye or hands.
  • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
  • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
  • Iopidine is usually given prior to, and right after laser surgery.
  • May also be used in conjunction with another eye drop for better control of eye pressure
Learn more
More about pilocarpineSide effectsAlternativesFDA package insert
More about IopidineSide effectsFDA package insert