Compare Plavix vs. Heparin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Plavix
(Clopidogrel)

Heparin

Prevents blood clots. Plavix (Clopidogrel) works well to prevent blood clots and heart complications, but watch out for drug interactions.Prevents blood clots. Heparin is a good anticoagulant that prevents blood clots. However, you'll need to get frequent blood tests to make sure it's working well.
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Reviews & ratings
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Button Group. All currently active
5.002949852507375Plavix
Reviews for Plavix (Clopidogrel)
59%
of people say Plavix (Clopidogrel) is worth it
49%
say it works well
16%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
PlavixHeparin
  • Minor bleeding 3%
  • Major bleeding 1%
  • Any noncerebral bleeding 1%
More Plavix side effects »

We haven’t found good data for Heparin side effects.

FDA side effect reports for Heparin »
How it works
PlavixHeparin
Plavix (Clopidogrel) is an antiplatelet blood thinner. It prevents blood platelets from working, which makes it harder for your body to form blood clots.Heparin is an anticoagulant that binds with proteins and platelets to stop blood clots from being made and traveling to the brain, heart, and lungs.
Type of medication
PlavixHeparin
Anticoagulant
Anti-platelet
Prescription only
Anticoagulant
Heparin
Prescription only
Available as
PlavixHeparin
  • Pill
  • Injection
Used for (click to learn more)
PlavixHeparin
Risk factors for serious side effects
PlavixHeparin
  • Genetic variation (CYP2C19 poor metabolizer)
  • Drug-interactions
  • Age greater than 65
  • History of gastrointestinal bleeding
  • High blood pressure
  • Liver problems
  • Drug interactions
  • Certain genetic disposition
    Detailed Plavix (Clopidogrel) risks & warnings »
    • History of bleeding problems
    • Severe high blood pressure
    • Older age
    • Heparin-induced thrombocytopenia
    Detailed Heparin risks & warnings »
    Pregnancy category
    PlavixHeparin
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    PlavixHeparin
    • Thins your blood to protect your heart after a heart attack or after a procedure on your heart.
    • Studies have shown clopidogrel lowers your risk of death or further heart complications.
    • Safe to use in pregnancy and if you're breast feeding.
    • There are other medications that can help stop unexpected bleeding while taking Heparin.
    • Available as a generic medication.
    • Usually used in the hospital, but can be given at home too.
    Downsides and risks
    PlavixHeparin
    • Raises your risk of bleeding and bruising.
    • Lots of interactions with other drugs or supplements. Always check with your doctor or pharmacist before starting any new meds.
    • Doesn't work well for people with certain genetic variations.
    • You'll need to get labs/blood draws done on a regular basis to make sure the drug is working and to make sure you don't get unexpected side effects.
    • You can be at higher risk for bleeding or clotting while taking Heparin compared to other anticoagulants.
    Tips from our pharmacists for people taking the medication
    PlavixHeparin
    • Thins your blood to prevent clots from forming or getting bigger. Doesn't break up existing clots.
    • Can raise your risk of bleeding or bruising.
    • Take it exactly as instructed.
    • Interacts with a lot of medicines and supplements. Don't start any new meds without talking to your doctor.
    • Let your doctor know about any fever, weakness, or unusual bleeding or bruising.
    • Make sure to change where you inject Heparin every time.
    • Don't take aspirin or other anti-inflammatory medications without talking to your doctor first.
    • You will have to do regular blood draws or labs to make sure that Heparin is working for you.
    Learn more
    More about PlavixSide effectsReviews & ratingsAlternativesFDA package insert
    More about HeparinSide effectsReviews & ratingsAlternativesFDA package insert