Compare Plavix vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Plavix
(Clopidogrel)

Pradaxa
(Dabigatran)

Prevents blood clots. Plavix (Clopidogrel) works well to prevent blood clots and heart complications, but watch out for drug interactions.Prevents blood clots. Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.
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Reviews & ratings
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5.002949852507375Plavix
Reviews for Plavix (Clopidogrel)
59%
of people say Plavix (Clopidogrel) is worth it
49%
say it works well
16%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
PlavixPradaxa
  • Minor bleeding 3%
  • Major bleeding 1%
  • Any noncerebral bleeding 1%
More Plavix side effects »

The Pradaxa FDA package insert doesn’t have numbers about how common side effects are.

More about Pradaxa side effects »
How it works
PlavixPradaxa
Plavix (Clopidogrel) is an antiplatelet blood thinner. It prevents blood platelets from working, which makes it harder for your body to form blood clots.Pradaxa (Dabigatran) is an anticoagulant that stops the formation of blood clots.
Type of medication
PlavixPradaxa
Anticoagulant
Anti-platelet
Prescription only
Anticoagulant
Thrombin inhibitor
Prescription only
Available as
PlavixPradaxa
  • Pill
  • Pill
Used for (click to learn more)
PlavixPradaxa
Risk factors for serious side effects
PlavixPradaxa
  • Genetic variation (CYP2C19 poor metabolizer)
  • Drug-interactions
  • Age greater than 65
  • History of gastrointestinal bleeding
  • High blood pressure
  • Liver problems
  • Drug interactions
  • Certain genetic disposition
    Detailed Plavix (Clopidogrel) risks & warnings »
    • Stopping Pradaxa (Dabigatran) too soon
    • Spinal tap
    • Anesthesia along the spine (epidural anesthesia)
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
    • Drug interactions
    • Taking with NSAIDs, aspirin, or other blood-thinning medicines
      • Artificial heart valve
      Detailed Pradaxa (Dabigatran) risks & warnings »
      Pregnancy category
      PlavixPradaxa
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      PlavixPradaxa
      • Thins your blood to protect your heart after a heart attack or after a procedure on your heart.
      • Studies have shown clopidogrel lowers your risk of death or further heart complications.
      • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
      • Doesn't require regular blood tests or frequent dose changes.
      • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
      Downsides and risks
      PlavixPradaxa
      • Raises your risk of bleeding and bruising.
      • Lots of interactions with other drugs or supplements. Always check with your doctor or pharmacist before starting any new meds.
      • Doesn't work well for people with certain genetic variations.
      • Not available as generic.
      • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
      • Can't take during pregnancy.
      Tips from our pharmacists for people taking the medication
      PlavixPradaxa
      • Thins your blood to prevent clots from forming or getting bigger. Doesn't break up existing clots.
      • Can raise your risk of bleeding or bruising.
      • Take it exactly as instructed.
      • Interacts with a lot of medicines and supplements. Don't start any new meds without talking to your doctor.
      • Let your doctor know about any fever, weakness, or unusual bleeding or bruising.
      • Pradaxa (Dabigatran) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
      • When taking Pradaxa (Dabigatran), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
      • Take this exactly as your doctor or pharmacist tells you to.
      • Take with a full glass of water. Swallow the capsule whole. Don't chew, break, or open the capsule.
      Learn more
      More about PlavixSide effectsReviews & ratingsAlternativesFDA package insert
      More about PradaxaSide effectsReviews & ratingsAlternativesFDA package insert