Compare Plendil vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Plendil
(Felodipine)

Catapres
(Clonidine)

Coming soon.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
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Reviews & ratings
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Reviews for Catapres (Clonidine)
42%
8% vs. Plendil (Felodipine)
33%
17% vs. Plendil (Felodipine)
34%
+16% vs. Plendil (Felodipine)
Side effects
PlendilCatapres

We haven’t found good data for Plendil side effects.

FDA side effect reports for Plendil »

The Catapres FDA package insert doesn’t have numbers about how common side effects are.

More about Catapres side effects »
How it works
PlendilCatapres
Coming soon.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.
Type of medication
PlendilCatapres
Coming soon.
Antihypertensive
Alpha agonist
Prescription only
Available as
PlendilCatapres
  • Extended release
  • Pill
  • Extended release
  • Patch
Used for (click to learn more)
PlendilCatapres
  • Hypertension
Risk factors for serious side effects
PlendilCatapres
Coming soon.
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Catapres (Clonidine) risks & warnings »
Pregnancy category
PlendilCatapres
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
PlendilCatapres
Coming soon.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
Downsides and risks
PlendilCatapres
Coming soon.
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
PlendilCatapres
Coming soon.
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Don't stop taking this medicine suddenly.
  • Extended release tablet also used to treat ADHD.
Learn more
More about PlendilSide effectsReviews & ratingsFDA package insert
More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert