Compare felodipine vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

felodipine

Coreg
(Carvedilol)

Lowers blood pressure. Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
Reviews & ratings
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Have you used Plendil (felodipine)?
Worth itNot sureNot worth it
Reviews for Coreg
53%
-53% worse vs. felodipine
46%
-46% worse vs. felodipine
18%
+18% better vs. felodipine
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Side effects
felodipineCoreg
  • Tingling sensations 1%
  • Runny nose 2%
  • Sneezing 2%
  • Rash 1%
  • Weakness 1%
  • Upset stomach 3%
  • Colds or flu 2%
  • Flushing 3%
More felodipine side effects »
  • Edema peripheral 1%
  • Edema dependent 2%
  • Hypercholesterolemia 1%
  • Digoxin level increased 1%
  • Edema generalized 2%
  • Vision abnormal 3%
  • Vomiting 2%
More Coreg side effects »
How it works
felodipineCoreg
Plendil (felodipine) is a calcium channel blocker. It lowers blood pressure by relaxing heart tissue and lowering pressure in blood vessels, which causes your blood pressure to go down.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
felodipineCoreg
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
felodipineCoreg
  • Extended release
  • Pill
  • Extended release
Used for
felodipineCoreg
Risk factors for serious side effects
felodipineCoreg
  • Over age 65
  • Taking in combination with a beta-blocker
  • Liver disease
  • History of heart failure
Detailed Plendil (felodipine) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (Carvedilol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
felodipineCoreg
  • Plendil (felodipine) can be taken without food or with a light low fat meal.
  • Take it with food.
  • You have to take Carvedilol with food.
Upsides and benefits
felodipineCoreg
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides and risks
felodipineCoreg
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
felodipineCoreg
  • Can cause swelling in your legs or ankles.
  • Can also cause swelling in your gums.
  • Plendil (felodipine) can be taken without food or with a light low fat meal.
  • Avoid grapefruit and grapefruit juice while taking Plendil (felodipine).
  • You might feel lightheaded or dizzy when first starting Plendil (felodipine).
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
Learn more
More about felodipineSide effectsAlternativesFDA package insert
Have you used Plendil (felodipine)?
Worth itNot sureNot worth it
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it