Compare Pradaxa vs. Xarelto

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pradaxa (Dabigatran)

Prescription only

Xarelto (rivaroxaban)

Prescription only
Prevents blood clots.

Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.

Prevents blood clots.

Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.

3.5/ 5 average rating with 22 reviewsforXarelto
Upsides
  • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
  • Doesn't require regular blood tests or frequent dose changes.
  • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
  • Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
  • Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
Downsides
  • Not available as generic.
  • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
  • Can't take during pregnancy.
  • Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
  • Xarelto (rivaroxaban) isn't available as a generic medication.
  • There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
  • You can't take Xarelto (rivaroxaban) if you are pregnant.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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22 reviews so far
45%
saidit'sworth it
45%
saiditworked well
9%
saidit'sa big hassle

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Side effects
10possible side effects
  • GI side effect
    35%
  • Any side effect
    21%
  • Any bleed
    20%
  • Dyspepsia
    8%
  • Major gastrointestinal bleed
    6%
  • Major bleed
    3%
  • GI bleed
    3%
  • Gastritis-like symptoms
    3%
  • Life-threatening bleed
    2%
  • Gastrointestinal bleed
    2%
See more detailed side effects
2possible side effects
  • Major bleeding needing transfusion
    4%
  • Bleeding in the stomach & intestines
    2%
See more detailed side effects
Risks and risk factors
  • Blood clots
    • Stopping Pradaxa (Dabigatran) too soon
  • Blood clot in the spine
    • Spinal tap
    • Anesthesia along the spine (epidural anesthesia)
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Unusual bleeding
    • Drug interactions
    • Taking with NSAIDs, aspirin, or other blood-thinning medicines
  • Stomach or intestinal problems
  • Increased risk of stroke or bleeding
    • Artificial heart valve
See more detailed risks and warnings
  • Blood clots and stroke
    • Stopping Xarelto (rivaroxaban) too soon
    • Artificial heart valve
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Drug interactions
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings