Compare Pradaxa vs. Xarelto

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pradaxa
(Dabigatran)

Xarelto
(Rivaroxaban)

Prevents blood clots. Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.Prevents blood clots. Xarelto (Rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Pradaxa (Dabigatran)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Xarelto (Rivaroxaban)?
Worth itNot sureNot worth it
Side effects
PradaxaXarelto

The Pradaxa FDA package insert doesn’t have numbers about how common side effects are.

More about Pradaxa side effects »
  • Back pain 3%
More Xarelto side effects »
How it works
PradaxaXarelto
Pradaxa (Dabigatran) is an anticoagulant that stops the formation of blood clots.Xarelto (Rivaroxaban) is an anticoagulant that stops the formation of blood clots.
Type of medication
PradaxaXarelto
Anticoagulant
Thrombin inhibitor
Prescription only
Anticoagulant
Factor Xa inhibitor
Prescription only
Available as
PradaxaXarelto
  • Pill
  • Pill
Used for (click to learn more)
PradaxaXarelto
Risk factors for serious side effects
PradaxaXarelto
  • Stopping Pradaxa (Dabigatran) too soon
  • Spinal tap
  • Anesthesia along the spine (epidural anesthesia)
  • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Drug interactions
  • Taking with NSAIDs, aspirin, or other blood-thinning medicines
    • Artificial heart valve
    Detailed Pradaxa (Dabigatran) risks & warnings »
    • Stopping Xarelto (Rivaroxaban) too soon
    • Artificial heart valve
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Drug interactions
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
    • Current kidney problems
    • Current liver problems
    Detailed Xarelto (Rivaroxaban) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    PradaxaXarelto
    No food related info.
    • Xarelto (Rivaroxaban) doesn't have as many food interactions as compared to other anticoagulants like warfarin (Coumadin).
    • Take Xarelto (Rivaroxaban) with food and a full glass of water.
    • As with all blood thinners, it will take a little longer for your blood to clot if you're bleeding and on Xarelto (Rivaroxaban). Call your doctor if you notice bleeding that won't stop, a bruise that won't go away or gets worse, pink or brown urine, bright red or dark tarry stool, nose bleeds, or coughing up blood.
    Kidneys and liver
    PradaxaXarelto
    No kidneys and liver related info.
    • Xarelto (Rivaroxaban) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor about possibly switching to a different medicine to prevent increased risk for side effects.
    Upsides and benefits
    PradaxaXarelto
    • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
    • Doesn't require regular blood tests or frequent dose changes.
    • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
    • Studies have shown that Xarelto (Rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and reducing bleeding.
    • Xarelto (Rivaroxaban) doesn't require regular blood testing or frequent dose adjustments.
    • Xarelto (Rivaroxaban) doesn't have as many food interactions as compared to other anticoagulants like warfarin (Coumadin).
    Downsides and risks
    PradaxaXarelto
    • Not available as generic.
    • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
    • Can't take during pregnancy.
    • Xarelto (Rivaroxaban) can increase your risk of bleeding. Call your doctor right away if there is blood in your phlegm, urine, or stool (look for black, tarry stools).
    • Xarelto (Rivaroxaban) isn't available as a generic medication.
    • There are no antidotes to stop bleeding caused by taking too much Xarelto (Rivaroxaban).
    • Can't take during pregnancy.
    Tips from our pharmacists for people taking the medication
    PradaxaXarelto
    • Pradaxa (Dabigatran) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
    • When taking Pradaxa (Dabigatran), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
    • Take this exactly as your doctor or pharmacist tells you to.
    • Take with a full glass of water. Swallow the capsule whole. Don't chew, break, or open the capsule.
    • Xarelto (Rivaroxaban) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
    • When taking Xarelto (Rivaroxaban), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
    • Take Xarelto (Rivaroxaban) with food and a full glass of water.
    • You can crush the tablets and mix with applesauce.
    Learn more
    More about PradaxaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Pradaxa (Dabigatran)?
    Worth itNot sureNot worth it
    More about XareltoSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Xarelto (Rivaroxaban)?
    Worth itNot sureNot worth it