Compare Prandin vs. Lantus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prandin
(repaglinide)

Lantus
(insulin glargine)

Lowers blood sugar. Prandin (repaglinide) works quickly to lower blood sugar, especially during mealtimes. However, it can cause hypoglycemia (low blood sugar) if you are not consistent with your diet and exercise schedule.Lowers blood sugar. Lantus (Insulin Glargine) is a long-acting insulin that provides all-day sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.
Reviews & ratings
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Have you used Prandin (repaglinide)?
Worth itNot sureNot worth it
Reviews for Lantus
67%
-67% worse vs. Prandin
51%
-51% worse vs. Prandin
14%
+14% better vs. Prandin
584 reviews
Have you used Lantus (insulin glargine)?
Worth itNot sureNot worth it
Side effects
PrandinLantus
  • Common cold 8%
  • Low blood sugar 24%
  • Headache 1%
  • Joint pain 3%
  • Sinusitis 4%
  • Diarrhea 3%
  • Back pain 1%
  • Swelling in arms and legs 5%
  • Heart failure 4%
More Prandin side effects »
  • Upper respiratory tract infection 22%
  • Infection 9%
  • Accidental injury 6%
  • Headache 6%
  • Edema peripheral 20%
  • Hypertension 20%
  • Sinusitis 19%
  • Influenza 19%
  • Cataract 18%
  • Bronchitis 15%
More Lantus side effects »
How it works
PrandinLantus
Prandin (repaglinide) stimulates your body to produce more insulin.Lantus (Insulin Glargine) is a long-acting insulin medicine for diabetes. It acts like the insulin that your body normally makes to process sugars and fats, and it keeps your blood sugar stable throughout the day.
Type of medication
PrandinLantus
Prescription onlyPrescription only
Available as
PrandinLantus
  • Pill
  • Injection
Used for
PrandinLantus
Risk factors for serious side effects
PrandinLantus
  • Alcoholism
  • Changes in meal pattern
  • Changes in exercise
  • Insulin
  • Other antidiabetic medications
Detailed Prandin (repaglinide) risks & warnings »
  • Insulin dose too high
  • Use of other blood sugar lowering medicines
  • Poor injection techniques
  • Unstable kidney functions
  • Unstable liver functions
Detailed Lantus (insulin glargine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
PrandinLantus
  • If you skip a meal, skip your dose to prevent hypoglycemia (low blood sugar).
  • Quickly and effectively lowers blood sugar during meal times.
No food related info.
Kidneys and liver
PrandinLantus
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
Weight
PrandinLantus
  • May cause some weight gain.
  • Can cause weight gain and low blood sugar.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
Upsides and benefits
PrandinLantus
  • Quickly and effectively lowers blood sugar during meal times.
  • Less likely to cause hypoglycemia (low blood sugar) than Starlix (nateglinide).
  • Good first-choice if you cannot tolerate metformin or add-on therapy if your blood sugars are not controlled on metformin alone.
  • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
  • Lantus is a long-lasting insulin that provides consistent, all-day sugar control with less risk of low blood sugar.
  • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
Downsides and risks
PrandinLantus
  • May cause some weight gain.
  • May cause hypoglycemia (low blood sugar).
  • Can frequently interfere with how other medicines work.
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
  • You have to take insulin by injection.
  • You have to check your blood sugar every day.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
  • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
Tips from our pharmacists for people taking the medication
PrandinLantus
  • Works quickly to lower blood sugar so should be taken 15 to 30 minutes before a meal.
  • If you skip a meal, skip your dose to prevent hypoglycemia (low blood sugar).
  • Maintain a regular diet and exercise schedule while on this medicine to prevent fluctuations in your blood sugar.
  • Long-acting insulin good for baseline blood sugar control.
  • Works in 1 hour and lasts about 24 hours.
  • Can cause weight gain and low blood sugar.
  • Make sure you and your family know the symptoms of low blood sugar: sweating, shakiness, weakness, fast heartbeat, nervousness, headache, blurry vision, trouble thinking clearly, or passing out.
  • Always have a good source of sugar nearby for low blood sugar episodes.
  • Take it at the same time every day.
  • Make sure you understand how to give yourself the injections.
  • Don't shake the vial or mix with another insulin. Store unopened vials in the refrigerator. Opened vials are good at room temperature for 28 days.
  • Check your blood sugar levels every day.
Learn more
More about PrandinSide effectsAlternativesFDA package insert
Have you used Prandin (repaglinide)?
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More about LantusSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lantus (insulin glargine)?
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