Compare pravastatin vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pravachol (pravastatin)

Prescription only

Lopid (Gemfibrozil)

Prescription only
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

4.8/ 7 average rating with 426 reviewsforpravastatin
Lowers triglyceride levels.

Lopid (Gemfibrozil) is a generically available medication that can lower triglyceride levels by up to 50%.

  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • Considered as a first choice medication for lowering triglyceride levels in the blood. Studies have shown it can reduce triglycerides by up to 50%.
  • Available as a generic.
  • Can be used with other medications, such as fish oil, to lower bad cholesterol and increase good cholesterol.
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • While Lopid (Gemfibrozil) has been shown to lower triglycerides, it has not been shown by itself to reduce the number of deaths caused by high cholesterol.
  • Can't be used with statins to lower cholesterol because of the risk of muscle and kidney damage.
Used for
Dosage forms
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  • Pill
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Side effects
10possible side effects
  • Muscle, joint or ligament/tendon pain    
  • Nausea, vomiting    
  • Diarrhea    
  • Headache    
  • Upper respiratory infection    
  • Chest pain    
  • Rash
  • Dizziness
  • Stuffy nose
  • Muscle damage
See more detailed side effects
The Lopid (Gemfibrozil) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Muscle damage

    Kidney disease

    ...and 4 more risk factors

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Harm to fetus


    ...and 1 more risk factors

  • Endocrine function

    Spironolactone use

    ...and 2 more risk factors

See more detailed risks and warnings
  • Muscle pain

    Taking Lopid (Gemfibrozil) with statins

  • Liver damage

    Past history of liver disease

  • Increased bleeding risk

    Taking Lopid (Gemfibrozil) with anticoagulants

See more detailed risks and warnings