Compare pravastatin vs. Lovastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pravachol (pravastatin)

Prescription only

Mevacor (Lovastatin)

Prescription only
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

3.5/ 5 average rating with 426 reviewsforpravastatin
Lowers cholesterol.

Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.

3.4/ 5 average rating with 89 reviewsforLovastatin
Upsides
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
Downsides
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
426 reviews so far
54%
saidit'sworth it
44%
saiditworked well
19%
saidit'sa big hassle

Have you used Pravachol (pravastatin)?

Leave a review
89 reviews so far
43%
saidit'sworth it
39%
saiditworked well
22%
saidit'sa big hassle

Have you used Mevacor (Lovastatin)?

Leave a review
Side effects
20possible side effects
  • Muscle, joint or ligament/tendon pain    
    10%
  • Nausea, vomiting    
    7%
  • Diarrhea    
    7%
  • Headache    
    6%
  • Upper respiratory infection    
    6%
  • Chest pain    
    5%
  • Rash
    5%
  • Dizziness
    4%
  • Stuffy nose
    4%
  • Muscle damage
    4%
  • Flatulence    
    3%
  • Indigestion, heartburn    
    3%
  • Fatigue    
    3%
  • Cough
    3%
  • Increased liver enzymes
    3%
  • Abdominal swelling
    2%
  • Influenza
    2%
  • Muscle pain
    2%
  • Sore throat
    2%
  • Bile duct disease
    2%
See more detailed side effects
2possible side effects
  • Elevations of CK levels
    11%
  • Increase in serum transaminases
    2%
See more detailed side effects
Risks and risk factors
  • Muscle damage
    • Kidney disease
    • An underactive thyroid
    • Over age 65
    • Female gender
    • Taking other medicines to lower your cholesterol
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Endocrine function
    • Spironolactone use
    • Cimetidine use
    • Ketoconazole use
See more detailed risks and warnings
  • Muscle pain
    • Kidney disease
    • High dose of Mevacor (Lovastatin)
    • Combining with certain cholesterol-lowering drugs
    • Older age and female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
  • Muscle weakness (autoimmune)
See more detailed risks and warnings