Compare pravastatin vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pravachol
(pravastatin)

Trilipix
(fenofibric acid)

Lowers cholesterol. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.Lowers cholesterol. Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.
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Coupons for pravastatin
Best available price for 30 (40mg) tablets of pravastatin
Coupons for Trilipix
Best available price for 30 (135mg) capsules of trilipix
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.76pravastatin
Reviews for pravastatin
54%
of people (All ages) say pravastatin is worth it
44%
say it works well
19%
say it's a big hassle
426 reviews
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
Reviews for Trilipix
50%
+4% better vs. pravastatin
22%
+22% better vs. pravastatin
25%
+6% better vs. pravastatin
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it
Side effects
pravastatinTrilipix
  • Upper respiratory infection 4%
  • Diarrhea 3%
  • Headache 2%
  • Chest pain 2%
  • Sore throat 2%
  • Rash 2%
  • Muscle pain 2%
More pravastatin side effects »
  • Headache 13%
  • Back pain 6%
  • Pain in extremity 5%
  • Ear, nose, or throat infection 5%
  • Nausea 4%
  • Common cold 4%
  • Diarrhea 4%
  • Joint pain 4%
  • Pain 4%
  • Dizziness 4%
More Trilipix side effects »
How it works
pravastatinTrilipix
Pravachol (pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Trilipix is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).
Type of medication
pravastatinTrilipix
Prescription onlyPrescription only
Available as
pravastatinTrilipix
  • Pill
  • Pill
  • Extended release
Used for
pravastatinTrilipix
Risk factors for serious side effects
pravastatinTrilipix
  • Kidney disease
  • An underactive thyroid
  • Over age 65
  • Female gender
  • Taking other medicines to lower your cholesterol
Detailed Pravachol (pravastatin) risks & warnings »
  • Taking Trilipix (Fenofibric Acid) with statins
  • Past history of liver disease
  • Taking Trilipix (Fenofibric Acid) with anticoagulants
Detailed Trilipix (fenofibric acid) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
pravastatinTrilipix
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
Upsides and benefits
pravastatinTrilipix
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides and risks
pravastatinTrilipix
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
Tips from our pharmacists for people taking the medication
pravastatinTrilipix
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Don't eat grapefruit and drink grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Also let your doctor know if you notice dark urine or yellowing of your eyes or skin.
  • You'll need to stop taking Pravachol (pravastatin) if you get pregnant.
  • Can be used with other medications to help lower cholesterol.
  • Lowers triglycerides.
  • Can raise your chance of getting colds and flu.
  • Call your doctor if you develop muscle or abdominal pain.
  • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
Learn more
More about pravastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
More about TrilipixSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it