Compare pravastatin vs. Vytorin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pravachol (pravastatin)

Prescription only
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

4.8/ 7 average rating with 426 reviewsforpravastatin
Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

4.4/ 7 average rating with 99 reviewsforVytorin
Upsides
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
Downsides
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$9.99
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Lowest price near you
$91.93
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Reviews
426 
54%
think this treatment is worth it
44%
think this treatment works well
19%
think this treatment is a hassle

Have you used Pravachol (pravastatin)?

Leave a review
99 
53%
think this treatment is worth it
36%
think this treatment works well
19%
think this treatment is a hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
Side effects
10possible side effects
  • Muscle, joint or ligament/tendon pain    
    10%
  • Nausea, vomiting    
    7%
  • Diarrhea    
    7%
  • Headache    
    6%
  • Upper respiratory infection    
    6%
  • Chest pain    
    5%
  • Rash
    5%
  • Dizziness
    4%
  • Stuffy nose
    4%
  • Muscle damage
    4%
See more detailed side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
Risks and warnings
  • Muscle damage

    Kidney disease

    ...and 4 more risk factors

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Harm to fetus

    Pregnancy

    ...and 1 more risk factors

  • Endocrine function

    Spironolactone use

    ...and 2 more risk factors

See more detailed risks and warnings
  • Muscle pain

    Asian patients taking high-dose niacin

  • Liver damage

    Past history of liver disease

    ...and 1 more risk factors

  • High blood sugar

    Diabetes

  • Harm to fetus

    Pregnancy

See more detailed risks and warnings