Compare pravastatin vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pravachol (pravastatin)

Prescription only

Zetia (ezetimibe)

Prescription only
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

4.8/ 7 average rating with 426 reviewsforpravastatin
Lowers cholesterol.

Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.

4.4/ 7 average rating with 128 reviewsforZetia
Upsides
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
Downsides
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$9.99
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$26.45
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Reviews
426 
54%
think this treatment is worth it
44%
think this treatment works well
19%
think this treatment is a hassle

Have you used Pravachol (pravastatin)?

Leave a review
128 
42%
think this treatment is worth it
34%
think this treatment works well
21%
think this treatment is a hassle

Have you used Zetia (ezetimibe)?

Leave a review
Side effects
10possible side effects
  • Muscle, joint or ligament/tendon pain    
    10%
  • Nausea, vomiting    
    7%
  • Diarrhea    
    7%
  • Headache    
    6%
  • Upper respiratory infection    
    6%
  • Chest pain    
    5%
  • Rash
    5%
  • Dizziness
    4%
  • Stuffy nose
    4%
  • Muscle damage
    4%
See more detailed side effects
8possible side effects
  • Diarrhea
    4%
  • Common cold
    4%
  • Sore throat
    4%
  • Sinus infection
    3%
  • Joint pain
    3%
  • Pain in arms and legs
    3%
  • Muscle pain
    3%
  • Abnormal liver tests
    3%
See more detailed side effects
Risks and warnings
  • Muscle damage

    Kidney disease

    ...and 4 more risk factors

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Harm to fetus

    Pregnancy

    ...and 1 more risk factors

  • Endocrine function

    Spironolactone use

    ...and 2 more risk factors

See more detailed risks and warnings
  • Muscle pain

    Taking Zetia (ezetimibe) with statins

  • Abnormal liver blood tests

    Past history of liver disease

    ...and 1 more risk factors

See more detailed risks and warnings