Compare Precose vs. Glucovance

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose
(Acarbose)

Glucovance
(Metformin / Glyburide)

Coming soon.Lowers blood sugar. Glucovance (Metformin / Glyburide) is a very effective combo medication to lower blood sugar when taking one medication alone isn't enough. It's likely to cause diarrhea for the first few weeks, and you can’t drink much alcohol.
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Reviews & ratings
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Side effects
PrecoseGlucovance

We haven’t found good data for Precose side effects.

FDA side effect reports for Precose »
  • Low blood sugar 35%
  • Gi side effects 14%
  • Diarrhea 11%
  • Abdominal pain 3%
  • Upper respiratory infection 3%
  • Nausea/vomiting 2%
  • Dizziness 2%
More Glucovance side effects »
How it works
PrecoseGlucovance
Coming soon.Glucovance (Metformin / Glyburide) is a combination medication for diabetes. Metformin lowers sugar (glucose) production in your body, decreases the amount of glucose getting into your blood, and makes your body more sensitive to insulin. Glyburide helps your body make more insulin to lower blood sugar.
Type of medication
PrecoseGlucovance
Coming soon.
Anti-diabetic
Biguanide
Sulfonylurea
Prescription only
Available as
PrecoseGlucovance
  • Pill
  • Pill
Used for (click to learn more)
PrecoseGlucovance
  • Diabetes mellitus type 2
Risk factors for serious side effects
PrecoseGlucovance
Coming soon.
  • Kidney problems
  • Liver problems
  • Congestive heart failure
  • Using contrast dye for procedures
  • Surgery
  • Alcohol use
    • Elderly
    • Use of other blood sugar lowering medicines
    • Alcohol use
    • Intense physical activity
    • History of sulfa reactions
      Detailed Glucovance (Metformin / Glyburide) risks & warnings »
      Pregnancy category
      PrecoseGlucovance
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.
      • Can't drink excessive amounts of alcohol or “binge drink” while taking this.
      • Try limiting the amount of alcohol you drink while taking this medication.
      Food
      No specific food-related info.
      • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
      Kidneys and liver
      No specific kidneys and liver-related info.
      • People with poor kidney function can't use Glucovance (Metformin / Glyburide).
      • Glucovance (Metformin / Glyburide) can cause lactic acidosis, a rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use Glucovance (Metformin / Glyburide). It may not be a good choice for people with kidney problems. Glucovance (Metformin / Glyburide) should be stopped 48 hours before and/or after surgery or procedure that'll use contrast dye.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.
      • Can cause some weight gain.
      Upsides and benefits
      PrecoseGlucovance
      Coming soon.
      • A combination medication that lowers your blood sugar in multiple ways. It's used by people who need tighter control of their blood sugar.
      • Can greatly lower A1c levels. The Hemoglobin A1c test measures your average blood sugar levels over the last few months.
      • Prevents harmful effects of high blood sugar levels on your organs and blood vessels.
      • Also lowers certain lipid (fat and cholesterol) levels.
      Downsides and risks
      PrecoseGlucovance
      Coming soon.
      • There's a higher risk of low blood sugar episodes than with other kinds of oral diabetes medications.
      • Most people will have nausea, stomach upset, or diarrhea in the first few weeks. You can lower these symptoms if you take it on a full stomach.
      • People with poor kidney function can't use Glucovance (Metformin / Glyburide).
      • Can't drink excessive amounts of alcohol or “binge drink” while taking this.
      • Can cause some weight gain.
      Tips from our pharmacists for people taking the medication
      PrecoseGlucovance
      Coming soon.
      • Can cause upset stomach, nausea, and diarrhea in the first couple of weeks.
      • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
      • Tell your doctor about any deep or rapid breathing, persistent nausea, vomiting, or stomach pain.
      • Try limiting the amount of alcohol you drink while taking this medication.
      • Check your blood sugar regularly.
      Learn more
      More about PrecoseSide effectsReviews & ratingsFDA package insert
      More about GlucovanceSide effectsAlternativesFDA package insert