Compare Precose vs. Glucovance

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose
(acarbose)

glyburide / metformin

Lowers blood sugar. Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.Lowers blood sugar. Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.
Reviews & ratings
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Have you used Precose (acarbose)?
Worth itNot sureNot worth it

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Have you used Glyburide / Metformin?
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Side effects
PrecoseGlucovance
  • Excessive gas 46%
  • Diarrhea 19%
  • Stomach pain 10%
More Precose side effects »
  • Upper respiratory infection 3%
  • Diarrhea 11%
  • Nausea/vomiting 2%
  • Stomach pain 3%
  • Dizziness 2%
  • Gastrointestinal side effects (diarrhea, nausea/vomiting, and stomach pain) 8%
  • Low blood sugar 8%
More Glucovance side effects »
How it works
PrecoseGlucovance
Precose (acarbose) stops an enzyme in your body from turning carbohydrates into sugar for energy. As a result, your body will absorb less sugar from the foods that you eat which will lead to lower blood sugar levels.Glyburide / Metformin combines 2 prescription medicines (glyburide and metformin) into 1 pill to help treat diabetes. Glyburide stimulates your body to release insulin to lower blood sugar. Metformin helps your body use its own insulin more effectively as well as lowers the amount of sugar your body naturally makes and absorbs from food.
Type of medication
PrecoseGlucovance
Prescription onlyPrescription only
Available as
PrecoseGlucovance
  • Pill
  • Pill
Used for
PrecoseGlucovance
Risk factors for serious side effects
PrecoseGlucovance
  • Using insulin or other medicines that stimulate insulin release
  • Those with kidney problems
  • Taking multiple medicines together
Detailed Precose (acarbose) risks & warnings »
  • History of kidney problems
  • History of liver problems
  • Those with congestive heart failure
  • Using contrast dye for procedures
  • Undergoing surgery
Detailed Glyburide / Metformin risks & warnings »
Pregnancy
Interactions
PrecoseGlucovance
  • Has relatively few interactions with other medicines.
No interactions related info.
Alcohol
PrecoseGlucovance
No alcohol related info.
  • Limit the amount of alcohol you drink while taking Glyburide / Metformin.
  • Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
Kidneys and liver
PrecoseGlucovance
  • Precose (acarbose) is not a recommended treatment option if you have bad kidney function or kidney problems. Your doctor will have you do a blood test to decide if this is the right medicine for you.
  • Not a good treatment option for those with kidney and/or liver problems.
Pain
PrecoseGlucovance
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
No pain related info.
Weight
PrecoseGlucovance
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • Can cause some weight gain.
Upsides and benefits
PrecoseGlucovance
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
  • Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
  • Can potentially lower your "bad cholesterol" levels.
  • Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
Downsides and risks
PrecoseGlucovance
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
  • Not a good treatment option for those with kidney and/or liver problems.
  • Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
  • Can cause some weight gain.
Tips from our pharmacists for people taking the medication
PrecoseGlucovance
  • Take Precose (acarbose) with the first bite of each main meal.
  • Don't take the medicine for the times you have skipped a meal.
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
  • You should continue to maintain a healthy diet, exercise regularly, and monitor your blood sugar levels while taking Precose (acarbose).
  • Your doctor will work with you to increase your dose gradually.
  • Carry glucose tablets with you at all times so that you can take them when your blood sugar drops to dangerously low levels. This is more likely to happen if you are also using insulin or a medicine that stimulates insulin release.
  • Check your blood sugar regularly.
  • Wear sunscreen and appropriate clothing to protect yourself from the sun.
  • Take the medicine with meals to prevent an upset stomach.
  • Tell your doctor right away if you experience rapid breathing, ongoing nausea, vomiting, or stomach pain.
  • Limit the amount of alcohol you drink while taking Glyburide / Metformin.
Learn more
More about PrecoseSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Precose (acarbose)?
Worth itNot sureNot worth it
More about GlucovanceSide effectsAlternativesFDA package insert
Have you used Glyburide / Metformin?
Worth itNot sureNot worth it