Compare Precose vs. Glucovance

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose (acarbose)

Prescription only

Glyburide / Metformin

Prescription only
Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

Lowers blood sugar.

Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.

Upsides
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
  • Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
  • Can potentially lower your "bad cholesterol" levels.
  • Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
Downsides
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
  • Not a good treatment option for those with kidney and/or liver problems.
  • Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
  • Can cause some weight gain.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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Side effects
3possible side effects
  • Excessive gas
    74%
  • Diarrhea
    31%
  • Stomach pain
    19%
See more detailed side effects
6possible side effects
  • Upper respiratory infection
    17%
  • Diarrhea
    17%
  • Headache
    9%
  • Nausea/vomiting
    8%
  • Stomach pain
    7%
  • Dizziness
    6%
See more detailed side effects
Risks and risk factors
  • Low blood sugar
    • Using insulin or other medicines that stimulate insulin release
  • Kidney function
    • Those with kidney problems
  • Interactions with other medicines
    • Taking multiple medicines together
See more detailed risks and warnings
  • Lactic acid build up in blood
    • History of kidney problems
    • History of liver problems
    • Those with congestive heart failure
    • Using contrast dye for procedures
    • Undergoing surgery
    • Drinking large amounts or frequent use of alcohol
  • Serious heart problems
  • Low blood sugar
    • Skipping meals or having inconsistent meal times
    • Drinking alcohol
    • Using other blood sugar-lowering medicine
    • People age 60 or older
    • Those with kidney and/or liver problems
  • Severe allergic reaction
    • History of allergy to sulfa-containing medicine
  • Breakdown of red blood cells
    • People with G6PD deficiency
See more detailed risks and warnings