Compare Precose vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose (acarbose)

Prescription only

Diabeta (glyburide)

Prescription only
Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

3.3/ 5 average rating with 110 reviewsforglyburide
Upsides
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle

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Side effects
3possible side effects
  • Excessive gas
    74%
  • Diarrhea
    31%
  • Stomach pain
    19%
See more detailed side effects
The Diabeta (glyburide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Low blood sugar
    • Using insulin or other medicines that stimulate insulin release
  • Kidney function
    • Those with kidney problems
  • Interactions with other medicines
    • Taking multiple medicines together
See more detailed risks and warnings
  • Low blood sugar
    • Over age 65
    • Kidney problems
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
  • Severe allergic reactions
    • History of sulfa allergies
See more detailed risks and warnings