Compare Precose vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose
(acarbose)

Diabeta
(glyburide)

Lowers blood sugar. Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.Lowers blood sugar. Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
Reviews & ratings
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Have you used Precose (acarbose)?
Worth itNot sureNot worth it
Reviews for glyburide
45%
+55% better vs. Precose
34%
+66% better vs. Precose
21%
+21% better vs. Precose
110 reviews
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it
Side effects
Precoseglyburide
  • Excessive gas 46%
  • Diarrhea 19%
  • Stomach pain 10%
More Precose side effects »
  • Nausea and heartburn 2%
  • Skin allergies 2%
More glyburide side effects »
How it works
Precoseglyburide
Precose (acarbose) stops an enzyme in your body from turning carbohydrates into sugar for energy. As a result, your body will absorb less sugar from the foods that you eat which will lead to lower blood sugar levels.Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.
Type of medication
Precoseglyburide
Prescription onlyPrescription only
Available as
Precoseglyburide
  • Pill
  • Pill
Used for
Precoseglyburide
Risk factors for serious side effects
Precoseglyburide
  • Using insulin or other medicines that stimulate insulin release
  • Those with kidney problems
  • Taking multiple medicines together
Detailed Precose (acarbose) risks & warnings »
  • Over age 65
  • Kidney problems
  • Use of other blood sugar lowering medicines
  • Alcohol
  • Intense physical activity
Detailed Diabeta (glyburide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
Precoseglyburide
  • Has relatively few interactions with other medicines.
No interactions related info.
Alcohol
Precoseglyburide
No alcohol related info.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Food
Precoseglyburide
No food related info.
  • Eat well-balanced meals to avoid low blood sugar.
Kidneys and liver
Precoseglyburide
  • Precose (acarbose) is not a recommended treatment option if you have bad kidney function or kidney problems. Your doctor will have you do a blood test to decide if this is the right medicine for you.
  • Not ideal for elderly or those with poor kidney function.
Pain
Precoseglyburide
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
No pain related info.
Weight
Precoseglyburide
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • Can cause weight gain, dizziness, or stomach upset.
  • Can cause weight gain (about 2 to 3 pounds).
Upsides and benefits
Precoseglyburide
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides and risks
Precoseglyburide
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Tips from our pharmacists for people taking the medication
Precoseglyburide
  • Take Precose (acarbose) with the first bite of each main meal.
  • Don't take the medicine for the times you have skipped a meal.
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
  • You should continue to maintain a healthy diet, exercise regularly, and monitor your blood sugar levels while taking Precose (acarbose).
  • Your doctor will work with you to increase your dose gradually.
  • Carry glucose tablets with you at all times so that you can take them when your blood sugar drops to dangerously low levels. This is more likely to happen if you are also using insulin or a medicine that stimulates insulin release.
  • Check your blood sugar regularly.
  • Eat well-balanced meals to avoid low blood sugar.
  • Works best if you take it 30 minutes before first main meal of the day.
  • Can cause weight gain, dizziness, or stomach upset.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Learn more
More about PrecoseSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Precose (acarbose)?
Worth itNot sureNot worth it
More about glyburideSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it