Compare Precose vs. Invokana

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Precose
(acarbose)

Invokana
(canagliflozin)

Lowers blood sugar. Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.Lowers blood sugar. Invokana (canagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.
Reviews & ratings
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Have you used Precose (acarbose)?
Worth itNot sureNot worth it
Reviews for Invokana
67%
+33% better vs. Precose
56%
+44% better vs. Precose
19%
+19% better vs. Precose
Have you used Invokana (canagliflozin)?
Worth itNot sureNot worth it
Side effects
PrecoseInvokana
  • Excessive gas 46%
  • Diarrhea 19%
  • Stomach pain 10%
More Precose side effects »
  • Yeast infection in women 8%
  • Urinary tract infections 2%
  • Increased urination 4%
  • Yeast infection in men 3%
  • Thirst 3%
  • Vaginal itching 2%
  • Constipation 1%
  • Abdominal pain 1%
More Invokana side effects »
How it works
PrecoseInvokana
Precose (acarbose) stops an enzyme in your body from turning carbohydrates into sugar for energy. As a result, your body will absorb less sugar from the foods that you eat which will lead to lower blood sugar levels.Invokana (canagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.
Type of medication
PrecoseInvokana
Prescription onlyPrescription only
Available as
PrecoseInvokana
  • Pill
  • Pill
Used for
PrecoseInvokana
Risk factors for serious side effects
PrecoseInvokana
  • Using insulin or other medicines that stimulate insulin release
  • Those with kidney problems
  • Taking multiple medicines together
Detailed Precose (acarbose) risks & warnings »
  • History of amputations 
  • Peripheral vascular disease (narrowed blood vessels)
  • Nerve problems
  • Diabetic foot ulcers 
  • History of kidney damage
Detailed Invokana (canagliflozin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
PrecoseInvokana
  • Has relatively few interactions with other medicines.
No interactions related info.
Alcohol
PrecoseInvokana
No alcohol related info.
  • Avoid if you are a heavy drinker of alcohol.
Food
PrecoseInvokana
No food related info.
  • Take once daily before your first meal of the day.
  • You only have to take Invokana (canagliflozin) once a day before meals.
Kidneys and liver
PrecoseInvokana
  • Precose (acarbose) is not a recommended treatment option if you have bad kidney function or kidney problems. Your doctor will have you do a blood test to decide if this is the right medicine for you.
  • Not for people with severe kidney problems.
Pain
PrecoseInvokana
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
  • Rarely, Invokana (canagliflozin) can hurt the kidneys. This is more likely to happen if you already have kidney damage, heart failure, or take certain medicines for blood pressure or anti-inflammatories (NSAIDs). Invokana (canagliflozin) can also lower your blood pressure since it makes you urinate more. Your doctor will check your kidneys by blood tests regularly, and might ask you to change how you take Invokana (canagliflozin). Make sure to stay hydrated to prevent low blood pressure and kidney problems.
Weight
PrecoseInvokana
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
No weight related info.
Upsides and benefits
PrecoseInvokana
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Lowers A1C (blood sugar) levels by 1%.
  • You only have to take Invokana (canagliflozin) once a day before meals.
  • Less likely to cause low blood sugar than other diabetes medicines.
  • Also available as a combination drug with metformin (Invokamet).
Downsides and risks
PrecoseInvokana
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
  • You're more likely to have broken bones, yeast infections and urinary tract infections with Invokana (canagliflozin).
  • There's a rare but serious risk of leg and foot amputations with Invokana (canagliflozin). Talk to your doctor if you develop new pain or infections in your feet.
  • Not for people with severe kidney problems.
  • Can raise your cholesterol.
  • Avoid if you are a heavy drinker of alcohol.
Tips from our pharmacists for people taking the medication
PrecoseInvokana
  • Take Precose (acarbose) with the first bite of each main meal.
  • Don't take the medicine for the times you have skipped a meal.
  • Causes side effects usually during the first few weeks of treatment including stomach pain, excessive gas, and diarrhea that will become less bothersome with time.
  • You should continue to maintain a healthy diet, exercise regularly, and monitor your blood sugar levels while taking Precose (acarbose).
  • Your doctor will work with you to increase your dose gradually.
  • Carry glucose tablets with you at all times so that you can take them when your blood sugar drops to dangerously low levels. This is more likely to happen if you are also using insulin or a medicine that stimulates insulin release.
  • Take once daily before your first meal of the day.
  • Invokana (canagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Can cause low blood sugar, so make sure to check your blood sugar if you don't feel well.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Invokana (canagliflozin).
Learn more
More about PrecoseSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Precose (acarbose)?
Worth itNot sureNot worth it
More about InvokanaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Invokana (canagliflozin)?
Worth itNot sureNot worth it