Compare Prednisolone vs. fludrocortisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pred Forte (Prednisolone)

Prescription only

Fludrocortisone

Prescription only
Treats eye redness and swelling.

Pred Forte (Prednisolone) is strong medicine for eye redness and swelling without exposing the rest of your body to the steroid medicine.

Treats electrolyte imbalance.

Fludrocortisone is one of the first choices used in Addison's disease to help maintain your electrolytes, but there are side effects.

Upsides
  • Decreases swelling and redness in your eyes.
  • Doesn't cause the same types of side effects that oral forms of steroids do.
  • Fludrocortisone is effective in correcting electrolyte imbalances associated with Addison's disease.
  • Generic is available.
  • Only need to take it once daily.
Downsides
  • Available only as a prescription medication.
  • You need good hand-eye coordination to get the eye drops into your eyes.
  • Can cause or worsen certain eye conditions.
  • Fludrocortisone can cause reactivation of old infections such as Hepatits B, C, or tuberculosis.
  • Fludrocortisone can make it easier for you to get sick.
  • Fludrocortisone can interact with other drugs and vaccines.
  • While on Fludrocortisone, you may need to have blood tests done for monitoring.
Used for
  • Addison's disease
  • Congential adrenal hyperplasia
Dosage forms
  • Eye drops
  • Pill
Price
Lowest price near you
$8.23
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Lowest price near you
$15.01
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Reviews
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Side effects
The Pred Forte (Prednisolone) FDA package insert doesn’t have numbers about how common side effects are.
The Fludrocortisone FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Cataracts

    Long-term use

  • Cornea hole

    Long-term use

  • Glaucoma

    Long-term use

    ...and 1 more risk factors

  • Infections in your eyes

    Long-term use

See more detailed risks and warnings
  • Lowered adrenal function

    Lowering dose or stopping too quickly especially after long-term treatment

    ...and 1 more risk factors

  • Increased risk for infections

    Taking other immunosuppressants

    ...and 4 more risk factors

  • Bone effects

    Dose of Fludrocortisone

    ...and 1 more risk factors

  • Stomach and intestinal problems

    History of stomach bleeding

    ...and 3 more risk factors

See more detailed risks and warnings