Compare Prednisolone vs. fludrocortisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Pred Forte
(prednisolone)

fludrocortisone

Treats eye redness and swelling. Pred Forte (Prednisolone) is strong medicine for eye redness and swelling without exposing the rest of your body to the steroid medicine.Treats electrolyte imbalance. Fludrocortisone is one of the first choices used in Addison's disease to help maintain your electrolytes, but there are side effects.
Reviews & ratings
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Have you used Pred Forte (prednisolone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Fludrocortisone?
Worth itNot sureNot worth it
Side effects
Prednisolonefludrocortisone

The Prednisolone FDA package insert doesn’t have numbers about how common side effects are.

More about Prednisolone side effects »

The fludrocortisone FDA package insert doesn’t have numbers about how common side effects are.

More about fludrocortisone side effects »
How it works
Prednisolonefludrocortisone
Pred Forte (Prednisolone) is a steroid that lowers your immune response to allergens and reduces eye redness and swelling.Fludrocortisone is a corticosteroid that is similar to what your body naturally makes. It is primarily used to maintain the sodium, potassium, and water balance in your body.
Type of medication
Prednisolonefludrocortisone
Prescription onlyPrescription only
Available as
Prednisolonefludrocortisone
  • Eye drops
  • Pill
Used for
Prednisolonefludrocortisone
  • Addisons Disease
Risk factors for serious side effects
Prednisolonefludrocortisone
  • Long-term use
  • History of glaucoma
Detailed Pred Forte (prednisolone) risks & warnings »
  • Lowering dose or stopping too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Taking other immunosuppressants
  • Long-term treatment
  • Not vaccinated against viral diseases
Detailed Fludrocortisone risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
Prednisolonefludrocortisone
No interactions related info.
  • Fludrocortisone can interact with other drugs and vaccines.
Pain
Prednisolonefludrocortisone
  • Let your doctor know if you have eye pain, pressure, infections, or changes in eye sight.
  • Taking Fludrocortisone increases the risk of injury to the lining of your stomach and intestine including irritation and tears. You should avoid alcohol/alcoholic beverages because it can worsen stomach irritation. Tell your doctor and get medical care right away if you have stomach pain or bloody/dark stools when you go to the bathroom.
Upsides and benefits
Prednisolonefludrocortisone
  • Decreases swelling and redness in your eyes.
  • Doesn't cause the same types of side effects that oral forms of steroids do.
  • Fludrocortisone is effective in correcting electrolyte imbalances associated with Addison's disease.
  • Generic is available.
  • Only need to take it once daily.
Downsides and risks
Prednisolonefludrocortisone
  • Available only as a prescription medication.
  • You need good hand-eye coordination to get the eye drops into your eyes.
  • Can cause or worsen certain eye conditions.
  • Fludrocortisone can cause reactivation of old infections such as Hepatits B, C, or tuberculosis.
  • Fludrocortisone can make it easier for you to get sick.
  • Fludrocortisone can interact with other drugs and vaccines.
  • While on Fludrocortisone, you may need to have blood tests done for monitoring.
Tips from our pharmacists for people taking the medication
Prednisolonefludrocortisone
  • Shake the eye drops well before using.
  • Press your finger gently on the inner corner of your eye after the drops are in to keep them there.
  • Wait 1 minute between each drop if you're giving yourself more than 1 drop.
  • If you have other eye drops, wait 5 minutes in between different sets of eye drops.
  • If your symptoms don't get better after 2 days, you may need to try a different medicine.
  • Let your doctor know if you have eye pain, pressure, infections, or changes in eye sight.
  • Take Fludrocortisone in the morning if you're taking it once a day, with or without food.
  • If you're on Fludrocortisone for a long period of time, watch out for any symptoms of illness, and let your doctor know right away.
  • Let your doctor know you're on this medicine before you receive any vaccines.
  • Fludrocortisone can re-activate any old infections you may have. Let your doctor know if you have or had hepatitis B, C, or tuberculosis.
Learn more
More about PrednisoloneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pred Forte (prednisolone)?
Worth itNot sureNot worth it
More about fludrocortisoneSide effectsAlternativesFDA package insert
Have you used Fludrocortisone?
Worth itNot sureNot worth it