Compare Prednisolone vs. Medrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats eye redness and swelling.

Pred Forte (Prednisolone) is strong medicine for eye redness and swelling without exposing the rest of your body to the steroid medicine.

Calms down your immune system.

Medrol (methylprednisolone) is very effective for controlling allergic reactions and many types of inflammatory conditions, but it is associated with serious and potentially life-threatening side effects if you have to take it for a long time.

3.7/ 5 average rating with 66 reviewsforMedrol
Upsides
  • Decreases swelling and redness in your eyes.
  • Doesn't cause the same types of side effects that oral forms of steroids do.
  • Medrol (methylprednisolone) is effective for treating a variety of conditions involving the immune system.
  • Can help improve energy and stimulate your appetite.
  • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
  • Medrol (methylprednisolone) is available in a generic form.
  • Available as blister packs that organize tablets into specific days and times for easier administration.
Downsides
  • Available only as a prescription medication.
  • You need good hand-eye coordination to get the eye drops into your eyes.
  • Can cause or worsen certain eye conditions.
  • Medrol (methylprednisolone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
  • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
  • If Medrol (methylprednisolone) is used for more than 2 weeks, you will need to work with a doctor to get off of the medicine by gradually decreasing the dose.
  • Medrol (methylprednisolone) can cause harm to an unborn baby, so it might not be a good option for pregnant women.
  • Might cause abnormal growth and development when used in children.
Used for
Dosage forms
  • Eye drops
  • Pill
  • Injection
Price
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Reviews
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66 reviews so far
59%
saidit'sworth it
53%
saiditworked well
23%
saidit'sa big hassle

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Side effects
The Pred Forte (Prednisolone) FDA package insert doesn’t have numbers about how common side effects are.
The Medrol (methylprednisolone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Cataracts
    • Long-term use
  • Cornea hole
    • Long-term use
  • Glaucoma
    • Long-term use
    • History of glaucoma
  • Infections in your eyes
    • Long-term use
See more detailed risks and warnings
  • Weakened immune system response to stress
    • Taking high doses of Medrol (methylprednisolone) for a long period of time
    • Young children
    • Stress such as trauma, injury, or infection
  • Increased risk for infections
    • Taking other medicines that weaken the immune system
    • Taking Medrol (methylprednisolone) for a long time
    • Those who are not vaccinated against viral illnesses
    • Coming into contact with people who have viral illness
    • History of bacterial or viral conditions
  • Changes in heart and kidney function
    • Those who had a recent heart attack
    • History of heart failure, high blood pressure, and kidney problems
  • Eye problems
    • Those with cataracts and/or glaucoma
    • History of herpes simplex in the eye
  • Harm to fetus (unborn baby)
    • Pregnant women
    • Women who can or plan to become pregnant
See more detailed risks and warnings