Compare prednisone vs. Allopurinol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Deltasone (prednisone)

Prescription only

Zyloprim (allopurinol)

Prescription only
Calms down your immune system.

Deltasone (prednisone) is effective for controlling allergic reactions and conditions involving an overactive immune system. It can quickly make you feel better, but Deltasone (prednisone) can cause serious complications and side effects if taken for a long time.

4.8/ 7 average rating with 540 reviewsforprednisone
Lowers uric acid levels in blood, and prevents gout flare-ups.

Zyloprim (allopurinol) works well to prevent gout attacks and is cheaper than some alternatives, but it takes a few weeks to start working.

5.0/ 7 average rating with 21 reviewsforAllopurinol
Upsides
  • Deltasone (prednisone) effectively treats a variety of conditions involving the immune system.
  • Can help improve energy and stimulate your appetite.
  • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
  • Good long-term treatment option for autoimmune disorders.
  • Deltasone (prednisone) is available in a generic form.
  • Zyloprim (allopurinol) works well to lower uric acid in the body.
  • It is available as a generic medication.
Downsides
  • Deltasone (prednisone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
  • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
  • If Deltasone (prednisone) is used for more than 2 weeks, you will need to work with a doctor to taper off the medicine by gradually decreasing the dose.
  • Deltasone (prednisone) can harm an unborn baby, so it's not a good option for pregnant women.
  • Zyloprim (allopurinol) can raise the number of gout attacks in the first few weeks.
  • It can take 2 to 6 weeks to feel the full effects of Zyloprim (allopurinol).
  • Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
Used for
Dosage forms
  • Pill
  • Delayed release pill
  • Liquid
  • Pill
  • Injection
Price
Lowest price near you
$3.28
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$4
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Reviews
540 
59%
think this treatment is worth it
45%
think this treatment works well
20%
think this treatment is a hassle

Have you used Deltasone (prednisone)?

Leave a review
21 
71%
think this treatment is worth it
52%
think this treatment works well
5%
think this treatment is a hassle

Have you used Zyloprim (allopurinol)?

Leave a review
Side effects
The Deltasone (prednisone) FDA package insert doesn’t have numbers about how common side effects are.
The Zyloprim (allopurinol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Physicial Dependence

    Taking high doses of Deltasone (prednisone) for a long period of time

    ...and 2 more risk factors

  • Increased risk for infections

    Taking other medicines that weaken the immune system

    ...and 4 more risk factors

  • Eye problems

    Those with cataracts and/or glaucoma

    ...and 1 more risk factors

  • Changes in heart and kidney function

    Those who had a recent heart attack

    ...and 1 more risk factors

  • Effects on bone

    Taking Deltasone (prednisone) at high doses and/or for a long period of time

    ...and 2 more risk factors

  • Stomach problems

    History of stomach bleeding

    ...and 3 more risk factors

See more detailed risks and warnings
  • Kidney stones

    History of kidney stones

  • Sleepiness or dizziness

    Taking other medications that also cause sleepiness

    ...and 3 more risk factors

See more detailed risks and warnings